Western Blot (WB)
(WB Suggested Anti-NAPSA AntibodyTitration: 1.0 ug/mlPositive Control: THP-1 Whole Cell)
Rabbit anti-Human NAPSA Polyclonal Antibody | anti-NAPSA antibody
NAPSA antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-NAPSA AntibodyTitration: 1.0 ug/mlPositive Control: THP-1 Whole Cell)
Western Blot (WB)
(WB Suggested Anti-NAPSA AntibodyTitration: 1.0 ug/mlPositive Control: THP-1 Whole Cell)
Target Description: The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]
Uniprot Description
NAPSA: May be involved in processing of pneumocyte surfactant precursors. Belongs to the peptidase A1 family.
Protein type: EC 3.4.23.-; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: extracellular space; lysosome
Molecular Function: aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity
Biological Process: cellular protein metabolic process; membrane protein proteolysis; protein catabolic process; surfactant homeostasis
Research Articles on NAPSA
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Product Notes
The NAPSA napsa (Catalog #AAA3216456) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NAPSA antibody - C-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NAPSA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the NAPSA napsa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PAGPFWILGD VFLGTYVAVF DRGDMKSSAR VGLARARTRG ADLGWGETAQ. It is sometimes possible for the material contained within the vial of "NAPSA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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