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Rabbit NAPA Polyclonal Antibody | anti-NAPA antibody

NAPA antibody

Gene Names
NAPA; SNAPA
Applications
Western Blot
Synonyms
NAPA; Polyclonal Antibody; NAPA antibody; Polyclonal NAPA; Anti-NAPA; alpha; N-ethylmaleimide-sensitive factor attachment protein; anti-NAPA antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
295
Applicable Applications for anti-NAPA antibody
Western Blot (WB)
Application Notes
Optimal conditions to be determined by the end user
Biological Significance
The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport.
Cross-Reactivity
Human, Mouse, Rat, Bovine, Dog, African Clawed Frog, Zebrafish
Immunogen
NAPA antibody was raised in rabbit using the N terminal of NAPA as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-NAPA antibody
Rabbit polyclonal NAPA antibody
Product Categories/Family for anti-NAPA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,233 Da
NCBI Official Full Name
alpha-soluble NSF attachment protein
NCBI Official Synonym Full Names
N-ethylmaleimide-sensitive factor attachment protein, alpha
NCBI Official Symbol
NAPA
NCBI Official Synonym Symbols
SNAPA
NCBI Protein Information
alpha-soluble NSF attachment protein
UniProt Protein Name
Alpha-soluble NSF attachment protein
Protein Family
UniProt Gene Name
NAPA
UniProt Synonym Gene Names
SNAPA; SNAP-alpha
UniProt Entry Name
SNAA_HUMAN

NCBI Description

This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]

Uniprot Description

SNAP-alpha: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Belongs to the SNAP family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: SNARE complex; membrane; vacuolar membrane; cytosol

Molecular Function: protein binding; syntaxin binding; soluble NSF attachment protein activity

Biological Process: neuron differentiation; synaptic transmission, glutamatergic; intra-Golgi vesicle-mediated transport; intracellular protein transport; apical protein localization; post-Golgi vesicle-mediated transport; brain development

Research Articles on NAPA

Similar Products

Product Notes

The NAPA napa (Catalog #AAA833755) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's NAPA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the NAPA napa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NAPA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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