Rabbit NANP Polyclonal Antibody | anti-NANP antibody

Rabbit Polyclonal to Human NANP

Cat. Num. AAA240049

• Gene Names: NANP; HDHD4; C20orf147; dJ694B14.3
• Reactivity: Gibbon, Dog, Gorilla, Hamster, Human, Mouse, Rabbit, Rat; Predicted Reactivity: Monkey, Bovine, Pig, Chicken (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: NANP; Polyclonal Antibody; Rabbit Polyclonal to Human NANP; Anti-NANP Antibody (Internal) IHC-plus; C20orf147; DJ694B14.3; Neu5Ac-9-Pase; HDHD4; Human NANP; anti-NANP antibody

• Host: Rabbit
• Reactivity: Gibbon, Dog, Gorilla, Hamster, Human, Mouse, Rabbit, Rat; Predicted Reactivity: Monkey, Bovine, Pig, Chicken (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human NANP. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 248

• Applicable Applications for anti-NANP antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (10 - 15 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic 16 amino acid peptide from internal region of human NANP. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Hamster, Panda, Rabbit (100%).
• Immunogen Type: Synthetic peptide
• Immunogen: NANP antibody was raised against synthetic 16 amino acid peptide from internal region of human NANP. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Hamster, Panda, Rabbit (100%); Marmoset, Bovine, Elephant, Pig, Opossum, Turkey, Chicken, Platypus (94%); Bat (88%); Lizard (81%).
• Antigen Modification: Internal
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-NANP antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Product Categories/Family for anti-NANP antibody

Family: Phosphatase

NCBI and Uniprot Product Information

• NCBI GI #: 23308749
• NCBI GeneID: 140838
• NCBI Accession #: NP_689880.1
• NCBI GenBank Nucleotide #: NM_152667.2
• UniProt Accession #: Q8TBE9; Q5JYN8; Q8TE97; Q9Y3N0; B3KP12
• Molecular Weight: 27,813 Da
• NCBI Official Full Name: N-acylneuraminate-9-phosphatase
• NCBI Official Synonym Full Names: N-acetylneuraminic acid phosphatase
• NCBI Official Symbol: NANP
• NCBI Official Synonym Symbols: HDHD4; C20orf147; dJ694B14.3
• NCBI Protein Information: N-acylneuraminate-9-phosphatase; Neu5Ac-9-Pase; haloacid dehalogenase-like hydrolase domain containing 4; haloacid dehalogenase-like hydrolase domain-containing protein 4
• UniProt Protein Name: N-acylneuraminate-9-phosphatase
• Protein Family: N-acylneuraminate-9-phosphatase
• UniProt Gene Name: NANP
• UniProt Synonym Gene Names: C20orf147; HDHD4
• UniProt Entry Name: NANP_HUMAN

Uniprot Description

HDHD4: Belongs to the HAD-like hydrolase superfamily. NANP family.

Protein type: Phosphatase (non-protein); Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 3.1.3.29

Chromosomal Location of Human Ortholog: 20p11.1

Cellular Component: cytosol

Molecular Function: N-acylneuraminate-9-phosphatase activity

Biological Process: N-acetylglucosamine biosynthetic process; N-acetylneuraminate biosynthetic process; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; dephosphorylation; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification