Western Blot (WB)
(Western BlotPositive WB detected in: U251 whole cell lysate, SH-SY5Y whole cell lysateAll lanes: Nox4 antibody at 3.3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 67 KDaObserved band size: 67 KDa)
Rabbit anti-Rat NADPH oxidase 4 Polyclonal Antibody | anti-Nox4 antibody
Rabbit anti-rat NADPH oxidase 4 polyclonal Antibody
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Western Blot (WB)
(Western BlotPositive WB detected in: U251 whole cell lysate, SH-SY5Y whole cell lysateAll lanes: Nox4 antibody at 3.3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 67 KDaObserved band size: 67 KDa)
Western Blot (WB)
(Western BlotPositive WB detected in: U251 whole cell lysate, SH-SY5Y whole cell lysateAll lanes: Nox4 antibody at 3.3ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 67 KDaObserved band size: 67 KDa)
NCBI and Uniprot Product Information
NCBI Description
enzyme involved in the production of reactive oxygen species in vascular smooth muscle cells [RGD, Feb 2006]
Uniprot Description
NOX4: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 4 displays an increased activity. Isoform 5 and isoform 6 display reduced activity. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus; Cell cycle regulation; Oxidoreductase; Membrane protein, multi-pass; EC 1.6.3.-; Membrane protein, integral
Research Articles on Nox4
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Product Notes
The Nox4 nox4 (Catalog #AAA1490653) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-rat NADPH oxidase 4 polyclonal Antibody reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NADPH oxidase 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Nox4 nox4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NADPH oxidase 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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