Rabbit anti-Human NaDC-3 Polyclonal Antibody
NaDC-3 (Sodium Dicarboxylate Transporter)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by affinity chromatography.
Synonyms
NaDC-3; Polyclonal Antibody; NaDC-3 (Sodium Dicarboxylate Transporter); Anti -NaDC-3 (Sodium Dicarboxylate Transporter); anti-NaDC-3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG1
Specificity
Recognizes human NaDC-3.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Purified by affinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.
Applicable Applications for anti-NaDC-3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1-10ug/ml using ECL.
ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml.
Dilution: Western Blot: 1-10ug/ml using ECL.
ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml.
Immunogen
Synthetic peptide corresponding to14aa from human NADC-3, conjugated to KLH. Epitope: ~C-terminal.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-NaDC-3 antibody
The sodium-dicarboxylate cotransporters (Solute carrier family 13), which transport succinate and other Krebs cycle intermediates, fall into 2 categories based on their substrate affinity, low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The two different Na+-coupled dicarboxylate transporters (NADC) have been identified in mammalian tissues. These are NADC1and NADC3 (NADC2 is found in C. Elegans). NADC1 is Na+-coupled, electrogenic, and exhibits low affinity for its dicarboxylatesubstrates. This isoform is expressedprimarily in the brush border membrane of intestinal and renalepithelial cells. The physiological function of NADC1 is to absorbthe intermediates of the citric acid cycle, such as citrate, succinate,-ketoglutarate, fumarate, and malate, in the intestine and kidney.NADC3 is also a Na+-coupled and electrogenic dicarboxylate transporter, but it exhibitsrelatively higher affinity for its substrates compared with NADC1.
Product Categories/Family for anti-NaDC-3 antibody
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Product Notes
The NaDC-3 (Catalog #AAA614275) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NaDC-3 (Sodium Dicarboxylate Transporter) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NaDC-3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot and ELISA. Dilution: Western Blot: 1-10ug/ml using ECL. ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml. Researchers should empirically determine the suitability of the NaDC-3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NaDC-3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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