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Immunohistochemistry (IHC) (Anti-MYOM2 / Myomesin 2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit anti-Mouse, Human MYOM2 / Myomesin 2 Polyclonal Antibody | anti-MYOM2 antibody

Anti-MYOM2 / Myomesin 2 Antibody (aa612-661) IHC-plus

Gene Names
MYOM2; TTNAP
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
MYOM2 / Myomesin 2; Polyclonal Antibody; Anti-MYOM2 / Myomesin 2 Antibody (aa612-661) IHC-plus; Rabbit Polyclonal (IgG) to Human MYOM2 / Myomesin 2; Human MYOM2 / Myomesin 2; M-protein; M-band protein; Myomesin (M-protein) 2 (165kD); Myomesin 2; Myomesin family member 2; TTNAP; Myomesin (M-protein) 2; 165kDa; Myomesin-2; anti-MYOM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
MYOM2 Antibody detects endogenous levels of total MYOM2 protein.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
1465
Applicable Applications for anti-MYOM2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:40000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)
Immunogen
MYOM2 / Myomesin 2 antibody was raised against synthetic peptide from human MYOM2 (aa612-661).
Immunogen Description
Synthetic peptide from human MYOM2 (aa612-661).
Antigen Modification
aa612-661
Target Species
Human
Preparation and Storage
Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Anti-MYOM2 / Myomesin 2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-MYOM2 / Myomesin 2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Western Blot (WB)

(Western blot of extracts from COS7/HT-29 cells, using MYOM2 Antibody. The lane on the right is treated with the synthesized peptide.)

Western Blot (WB) (Western blot of extracts from COS7/HT-29 cells, using MYOM2 Antibody. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-MYOM2 antibody
MYOM2 Antibody, M-protein Antibody, M-band protein Antibody, Myomesin (M-protein) 2 (165kD) Antibody, Myomesin 2 Antibody, Myomesin family member 2 Antibody, TTNAP Antibody, Myomesin (M-protein) 2, 165kDa Antibody, Myomesin-2 Antibody Description: The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
164,896 Da
NCBI Official Full Name
myomesin-2
NCBI Official Synonym Full Names
myomesin 2
NCBI Official Symbol
MYOM2
NCBI Official Synonym Symbols
TTNAP
NCBI Protein Information
myomesin-2
UniProt Protein Name
Myomesin-2
Protein Family
UniProt Gene Name
MYOM2
UniProt Entry Name
MYOM2_HUMAN

NCBI Description

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]

Uniprot Description

myomesin 2: Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

Protein type: Cytoskeletal; Contractile

Chromosomal Location of Human Ortholog: 8p23.3

Cellular Component: M band; mitochondrion

Molecular Function: protein binding; structural constituent of muscle

Biological Process: muscle contraction

Research Articles on MYOM2

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Product Notes

The MYOM2 myom2 (Catalog #AAA249721) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MYOM2 / Myomesin 2 Antibody (aa612-661) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYOM2 / Myomesin 2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA). ELISA (1:40000) IHC-P (10 ug/ml) WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the MYOM2 myom2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYOM2 / Myomesin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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