Western Blot (WB)
(Western blot analysis of MYH8 using HepG2 whole cell lysates)
Rabbit anti-Human MYH8 Polyclonal Antibody | anti-MYH8 antibody
MYH8 Antibody
Gene Names
MYH8; DA7; MyHC-pn; gtMHC-F; MyHC-peri
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
MYH8; Polyclonal Antibody; MYH8 Antibody; DA7; Fetal myosin heavy chain; gtMHC F; MYH8_HUMAN; MyHC peri; MyHC pn; MyHC-perinatal; Myosin heavy chain 8; Myosin heavy chain; skeletal muscle; perinatal; Myosin; heavy chain 8; heavy polypeptide 8; Myosin-8; anti-MYH8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
MYH8 antibody detects endogenous levels of total MYH8
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1937
Applicable Applications for anti-MYH8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human MYH8
Subcellular Location
Cytoplasm, Myofibril. Thick filaments of the myofibrils.
Predicted Cross Reactivity
Pig, Horse, Rabbit, Dog
Similarity
Pig (92%), Horse (100%), Rabbit (100%), Dog (83%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of MYH8 using HepG2 whole cell lysates)
Western Blot (WB)
(Western blot analysis of MYH8 using HepG2 whole cell lysates)
Related Product Information for anti-MYH8 antibody
Function: Muscle contraction.
Subunit Structure: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
Similarity: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Subunit Structure: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
Similarity: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 223 kDa
Predicted: 223 kDa
Predicted: 223 kDa
NCBI Official Full Name
myosin-8
NCBI Official Synonym Full Names
myosin heavy chain 8
NCBI Official Symbol
MYH8
NCBI Official Synonym Symbols
DA7; MyHC-pn; gtMHC-F; MyHC-peri
NCBI Protein Information
myosin-8
UniProt Protein Name
Myosin-8
Protein Family
UniProt Gene Name
MYH8
UniProt Synonym Gene Names
MyHC-perinatal
NCBI Description
Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009]
Uniprot Description
Muscle contraction.
Research Articles on MYH8
Similar Products
Product Notes
The MYH8 myh8 (Catalog #AAA9609965) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MYH8 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYH8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the MYH8 myh8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYH8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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