Western Blot (WB)
(Western blot analysis of lysates from A549 cells, using Myelodysplasia Syndrome 1 Antibody. The lane on the right is blocked with the synthesized peptide.)
Rabbit anti-Human Myelodysplasia Syndrome 1 Polyclonal Antibody | anti-MDS1 antibody
Myelodysplasia Syndrome 1 Antibody
Gene Names
MECOM; EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
Myelodysplasia Syndrome 1; Polyclonal Antibody; Myelodysplasia Syndrome 1 Antibody; MDS1 and EVI1 complex locus protein MDS1; Myelodysplasia syndrome 1 protein; Myelodysplasia syndrome-associated protein 1; MECOM; anti-MDS1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Myelodysplasia Syndrome 1 Antibody detects endogenous levels of total Myelodysplasia Syndrome 1 protein.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1,239
Applicable Applications for anti-MDS1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:1000
ELISA: 1:1000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human MECOM.
Immunogen Range
Jan-50
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Western Blot (WB)
(Western blot analysis of lysates from A549 cells, using Myelodysplasia Syndrome 1 Antibody. The lane on the right is blocked with the synthesized peptide.)
Western Blot (WB)
(Western blot analysis of lysates from A549 cells, using Myelodysplasia Syndrome 1 Antibody. The lane on the right is blocked with the synthesized peptide.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18 kDa
NCBI Official Full Name
MDS1 and EVI1 complex locus protein EVI1 isoform c
NCBI Official Synonym Full Names
MDS1 and EVI1 complex locus
NCBI Official Symbol
MECOM
NCBI Official Synonym Symbols
EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1
NCBI Protein Information
MDS1 and EVI1 complex locus protein EVI1
UniProt Protein Name
MDS1 and EVI1 complex locus protein MDS1
UniProt Gene Name
MECOM
UniProt Synonym Gene Names
MDS1
NCBI Description
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Research Articles on MDS1
Similar Products
Product Notes
The MDS1 mecom (Catalog #AAA9505205) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Myelodysplasia Syndrome 1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Myelodysplasia Syndrome 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:1000. Researchers should empirically determine the suitability of the MDS1 mecom for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Myelodysplasia Syndrome 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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