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Immunofluorescence (IF) (Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MYBPC2 antibody at 1:200 dilution.)

Rabbit MYBPC2 Polyclonal Antibody | anti-MYBPC2 antibody

MYBPC2 Antibody

Gene Names
MYBPC2; MYBPC; MYBPCF; fsMyBP-C
Applications
Immunofluorescence, Immunocytochemistry, Western Blot
Purity
Antigen-Affinity Chromatography
Synonyms
MYBPC2; Polyclonal Antibody; MYBPC2 Antibody; Affinity Purified Rabbit Polyclonal MYBPC2 Antibody; Polyclonal MYBPC2 antibody; Anti-MYBPC2 antibody; MYBPCF antibody; MYBPC antibody; fast-type muscle myosin-binding-protein C antibody; MYBPC 2; MYBPC 2 antibody; MYBPC-2 antibody; fast MyBP-C antibody; C-protein skeletal muscle fast isoform antibody; MYBPC-2; MGC163408 antibody; MYBPC2 antibody; anti-MYBPC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen-Affinity Chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
0.87 mg/ml (varies by lot)
Sequence Length
1141
Applicable Applications for anti-MYBPC2 antibody
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB)
Application Notes
IF: 1:100-1:200
WB: 1:500-1:3000
Immunogen
MYBPC2 antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 411 and 729 of MYBPC2
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunofluorescence (IF)

(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MYBPC2 antibody at 1:200 dilution.)

Immunofluorescence (IF) (Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using MYBPC2 antibody at 1:200 dilution.)

Western Blot (WB)

(Western blot analysis of 30 ug of whole cell lysate (A: Hela S3) using a 7.5% SDS PAGE gel and MYBPC2 antibody at a dilution of 1:500)

Western Blot (WB) (Western blot analysis of 30 ug of whole cell lysate (A: Hela S3) using a 7.5% SDS PAGE gel and MYBPC2 antibody at a dilution of 1:500)
Related Product Information for anti-MYBPC2 antibody
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Product Categories/Family for anti-MYBPC2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
128 kDa
NCBI Official Full Name
myosin-binding protein C, fast-type
NCBI Official Synonym Full Names
myosin binding protein C, fast type
NCBI Official Symbol
MYBPC2
NCBI Official Synonym Symbols
MYBPC; MYBPCF; fsMyBP-C
NCBI Protein Information
myosin-binding protein C, fast-type
UniProt Protein Name
Myosin-binding protein C, fast-type
Protein Family
UniProt Gene Name
MYBPC2
UniProt Synonym Gene Names
MYBPCF; Fast MyBP-C
UniProt Entry Name
MYPC2_HUMAN

NCBI Description

This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively. [provided by RefSeq, Jul 2012]

Uniprot Description

MYBPC2: Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Belongs to the immunoglobulin superfamily. MyBP family.

Protein type: Myosin-binding

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: cytosol

Molecular Function: protein binding; structural constituent of muscle; actin binding

Biological Process: cell adhesion; muscle filament sliding

Research Articles on MYBPC2

Similar Products

Product Notes

The MYBPC2 mybpc2 (Catalog #AAA5312032) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MYBPC2 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB). IF: 1:100-1:200 WB: 1:500-1:3000. Researchers should empirically determine the suitability of the MYBPC2 mybpc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYBPC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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