Rabbit anti-Human MYBBP1A Polyclonal Antibody | anti-MYBBP1A antibody
MYBBP1A Conjugated Antibody
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
NCBI and Uniprot Product Information
NCBI Description
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008]
Uniprot Description
MYBBP1A: may activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Binds to and represses JUN and MYB via the leucine zipper regions present in these proteins. Also binds to and represses PGC-1 (PPAR gamma coactivator-1): this interaction is abrogated when PGC-1 is phosphorylated by ERK1. Binds to and stimulates transcription by AhR. Binds to KPNA2. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on exportin 1. Predominantly nucleolar. Two alternatively spliced isoforms have been described.
Protein type: Nucleolus; DNA replication; DNA-binding; RNA-binding
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: NLS-dependent protein nuclear import complex; intracellular membrane-bound organelle; membrane; cytoplasm; nucleolus; nucleus
Molecular Function: protein binding; sequence-specific DNA binding; DNA-directed DNA polymerase activity; transcription corepressor activity; transcription factor binding
Biological Process: osteoblast differentiation; cellular response to glucose starvation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; nucleocytoplasmic transport; circadian regulation of gene expression; negative regulation of transcription, DNA-dependent
Research Articles on MYBBP1A
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Product Notes
The MYBBP1A mybbp1a (Catalog #AAA9448184) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MYBBP1A Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYBBP1A can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the MYBBP1A mybbp1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYBBP1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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