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Western Blot (WB) (MURC Antibody (N-term) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the MURC antibody detected MURC protein (arrow).)

Rabbit anti-Human, mouse MURC Polyclonal Antibody | anti-MURC antibody

MURC Antibody (N-term)

Gene Names
MURC; CAVIN4; cavin-4
Reactivity
Human, mouse
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MURC; Polyclonal Antibody; MURC Antibody (N-term); Muscle-related coiled-coil protein; Muscle-restricted coiled-coil protein; anti-MURC antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MURC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the N-terminal region of human MURC.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
87-116
Sequence Length
364
Applicable Applications for anti-MURC antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(MURC Antibody (N-term) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the MURC antibody detected MURC protein (arrow).)

Western Blot (WB) (MURC Antibody (N-term) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the MURC antibody detected MURC protein (arrow).)

Immunohistochemistry (IHC)

(MURC Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MURC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (MURC Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MURC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-MURC antibody
MURC induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.
Product Categories/Family for anti-MURC antibody
References
Tagawa, M., et al. Am. J. Physiol., Cell Physiol. 295 (2), C490-C498 (2008) :
Ogata, T., et al. Mol. Cell. Biol. 28(10):3424-3436(2008)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41899
NCBI Official Full Name
muscle-related coiled-coil protein
NCBI Official Synonym Full Names
muscle-related coiled-coil protein
NCBI Official Symbol
MURC
NCBI Official Synonym Symbols
CAVIN4; cavin-4
NCBI Protein Information
muscle-related coiled-coil protein
UniProt Protein Name
Muscle-related coiled-coil protein
UniProt Gene Name
MURC
UniProt Entry Name
MURC_HUMAN

NCBI Description

This gene encodes a protein containing two coiled-coil regions. The encoded protein promotes Rho/ROCK (Rho-kinase) signaling in cardiac muscles cells, and may facilitate myofibrillar organization. [provided by RefSeq, Jun 2013]

Uniprot Description

MURC: Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway. Belongs to the PTRF/SDPR family.

Chromosomal Location of Human Ortholog: 9q31.1

Cellular Component: cytoplasm; Z disc

Biological Process: muscle development; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cell differentiation

Research Articles on MURC

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Product Notes

The MURC murc (Catalog #AAA9206993) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 87-116. The MURC Antibody (N-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MURC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the MURC murc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MURC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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