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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gliomas using MBS7601659 (CRYM antibody) at dilution of 1:50)

Rabbit mu Crystallin Polyclonal Antibody | anti-CRYM antibody

mu Crystallin Rabbit Polyclonal

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
mu Crystallin; Polyclonal Antibody; mu Crystallin Rabbit Polyclonal; anti-CRYM antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
314
Applicable Applications for anti-CRYM antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Crystallin, mu
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gliomas using MBS7601659 (CRYM antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human gliomas using MBS7601659 (CRYM antibody) at dilution of 1:50)

Western Blot (WB)

(Y79 cells were subjected to SDS PAGE followed by western blot with MBS7601659 (CRYM antibody) at dilution of 1:400)

Western Blot (WB) (Y79 cells were subjected to SDS PAGE followed by western blot with MBS7601659 (CRYM antibody) at dilution of 1:400)

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
33,776 Da
NCBI Official Full Name
mu-crystallin
UniProt Protein Name
Ketimine reductase mu-crystallin
Protein Family
UniProt Gene Name
CRYM
UniProt Synonym Gene Names
THBP
UniProt Entry Name
CRYM_HUMAN

Uniprot Description

CRYM: Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors. Belongs to the ornithine cyclodeaminase family.

Protein type: EC 1.5.1.25; Lyase

Chromosomal Location of Human Ortholog: 16p12.2

Cellular Component: cytoplasm; mitochondrion; nucleus; peroxisomal matrix

Molecular Function: NADP binding; protein binding; protein homodimerization activity; thiomorpholine-carboxylate dehydrogenase activity; transcription corepressor activity

Biological Process: lysine catabolic process; negative regulation of transcription from RNA polymerase II promoter; sensory perception of sound; thyroid hormone metabolic process

Disease: Deafness, Autosomal Dominant 40

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Product Notes

The mu Crystallin crym (Catalog #AAA7601659) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The mu Crystallin Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's mu Crystallin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the mu Crystallin crym for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "mu Crystallin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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