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Western Blot (WB) (Western BlotPositive WB detected in: HL-60 whole cell lysate,K562 whole cell lysateAll lanes: MTERF1 antibody at 2.6ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 46 KDaObserved band size: 46 KDa)

Rabbit anti-Human MTERF1 Polyclonal Antibody | anti-MTERF1 antibody

MTERF1 Antibody

Gene Names
MTERF1; MTERF
Reactivity
Human
Applications
ELISA, Western Blot
Purity
>95%, Protein G purified
Synonyms
MTERF1; Polyclonal Antibody; MTERF1 Antibody; Transcription termination factor 1; mitochondrial; Mitochondrial transcription termination factor 1; mTERF; mTERF1; MTERF; anti-MTERF1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
379
Applicable Applications for anti-MTERF1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1: 500-1: 5000
Immunogen
Recombinant Human Transcription termination factor 1, mitochondrial protein (63-232AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Conjugation
Non-conjugated
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western BlotPositive WB detected in: HL-60 whole cell lysate,K562 whole cell lysateAll lanes: MTERF1 antibody at 2.6ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 46 KDaObserved band size: 46 KDa)

Western Blot (WB) (Western BlotPositive WB detected in: HL-60 whole cell lysate,K562 whole cell lysateAll lanes: MTERF1 antibody at 2.6ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 46 KDaObserved band size: 46 KDa)
Related Product Information for anti-MTERF1 antibody
Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,778 Da
NCBI Official Full Name
transcription termination factor 1, mitochondrial isoform 2
NCBI Official Synonym Full Names
mitochondrial transcription termination factor 1
NCBI Official Symbol
MTERF1
NCBI Official Synonym Symbols
MTERF
NCBI Protein Information
transcription termination factor 1, mitochondrial
UniProt Protein Name
Transcription termination factor 1, mitochondrial
UniProt Gene Name
MTERF1
UniProt Synonym Gene Names
MTERF; mTERF; mTERF1
UniProt Entry Name
MTEF1_HUMAN

NCBI Description

This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008]

Uniprot Description

MTERF: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity. Belongs to the mTERF family.

Chromosomal Location of Human Ortholog: 7q21.2

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: double-stranded DNA binding; protein binding

Biological Process: DNA geometric change; mitochondrion organization and biogenesis; termination of mitochondrial transcription; transcription termination

Research Articles on MTERF1

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Product Notes

The MTERF1 mterf1 (Catalog #AAA7050675) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MTERF1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MTERF1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1: 500-1: 5000. Researchers should empirically determine the suitability of the MTERF1 mterf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MTERF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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