Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MSH4 Polyclonal Antibody at dilution 1:50)
Rabbit MSH4 Polyclonal Antibody | anti-MSH4 antibody
MSH4 Polyclonal Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MSH4 Polyclonal Antibody at dilution 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MSH4 Polyclonal Antibody at dilution 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MSH4 Polyclonal Antibody at dilution 1:50)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MSH4 Polyclonal Antibody at dilution 1:50)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. [provided by RefSeq, Aug 2011]
Uniprot Description
MSH4: Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis. Belongs to the DNA mismatch repair MutS family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 1p31
Cellular Component: synaptonemal complex; nucleus
Molecular Function: DNA-dependent ATPase activity; protein binding; DNA binding; damaged DNA binding; ATP binding; mismatched DNA binding
Biological Process: homologous chromosome segregation; ovarian follicle development; meiotic recombination; female gamete generation; spermatogenesis; chiasma formation; meiotic mismatch repair
Research Articles on MSH4
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Product Notes
The MSH4 msh4 (Catalog #AAA2522871) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MSH4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MSH4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:100-1:300. Researchers should empirically determine the suitability of the MSH4 msh4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MSH4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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