Rabbit anti-Human MRTO4 Polyclonal Antibody | anti-MRTO4 antibody

MRTO4, NT (MRTO4, C1orf33, MRT4, mRNA turnover protein 4 homolog) (FITC)

Cat. Num. AAA6322365

• Gene Names: MRTO4; MRT4; C1orf33; dJ657E11.4
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MRTO4; Polyclonal Antibody; NT (MRTO4; C1orf33; MRT4; mRNA turnover protein 4 homolog) (FITC); mRNA turnover protein 4 homolog; anti-MRTO4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-MRTO4 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: MRTO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of human MRTO4.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MRTO4 Antibody (N-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MRTO4 antibody detected the MRTO4 protein (arrow).)

Related Product Information for anti-MRTO4 antibody

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq].

Product Categories/Family for anti-MRTO4 antibody

Antibodies; Ribosomal Proteins

References

Michalec, B., et al. Int. J. Biochem. Cell Biol. 42(5):736-748(2010). Rose, J. Phd, et al. Mol. Med. (2010). In press: Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002). Andersen, J.S., et al. Curr. Biol. 12(1):1-11(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 118572609
• NCBI GeneID: 51154
• NCBI Accession #: NP_057267.2
• NCBI GenBank Nucleotide #: NM_016183
• UniProt Accession #: Q9UKD2; Q5TG55; Q96SS6; Q9BPV9; B3KNB3
• Molecular Weight: 27,560 Da
• NCBI Official Full Name: Homo sapiens mRNA turnover 4 homolog (S. cerevisiae) (MRTO4), mRNA
• NCBI Official Synonym Full Names: mRNA turnover 4 homolog (S. cerevisiae)
• NCBI Official Symbol: MRTO4
• NCBI Official Synonym Symbols: MRT4; C1orf33; dJ657E11.4
• NCBI Protein Information: mRNA turnover protein 4 homolog; 60S acidic ribosomal protein PO; MRT4, mRNA turnover 4, homolog; ribosome assembly factor MRTO4
• UniProt Protein Name: mRNA turnover protein 4 homolog
• Protein Family: mRNA turnover protein
• UniProt Gene Name: MRTO4
• UniProt Entry Name: MRT4_HUMAN

NCBI Description

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008]

Uniprot Description

MRTO4: Involved in mRNA turnover and ribosome assembly. Belongs to the ribosomal protein L10P family.

Protein type: Nucleolus; RNA-binding

Chromosomal Location of Human Ortholog: 1p36.13

Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; nucleolus; nucleus

Biological Process: ribosome biogenesis and assembly