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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using MRPS21 antibody.)

Rabbit MRPS21 Polyclonal Antibody | anti-MRPS21 antibody

MRPS21 antibody

Gene Names
MRPS21; MDS016; RPMS21; MRP-S21
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Synonyms
MRPS21; Polyclonal Antibody; MRPS21 antibody; Polyclonal MRPS21; Anti-MRPS21; 28S ribosomal protein S21; mitochondrial; MDS016; mitochondrial 28S ribosomal protein S21; mitochondrial ribosomal protein S21; MRP-S21; RPMS21; RT21; S21mt; anti-MRPS21 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
MRPS21 antibody detects endogenous levels of total MRPS21 protein
Form/Format
Supplied in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
87
Applicable Applications for anti-MRPS21 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:100
IF: 1:100-1:500
ELISA: 1:40000
Biological Significance
MRPS21 is a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion.
Cross-Reactivity
Mouse, Rat
Immunogen
MRPS21 antibody was raised in Rabbit using a synthesized peptide derived from internal of human MRPS21 as the immunogen
Preparation and Storage
Store at -20 degree C for 1 year

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using MRPS21 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using MRPS21 antibody.)

Western Blot (WB)

(Western blot analysis of extracts from COS cells, using MRPS21 antibody)

Western Blot (WB) (Western blot analysis of extracts from COS cells, using MRPS21 antibody)
Related Product Information for anti-MRPS21 antibody
Purified Rabbit polyclonal MRPS21 antibody
Product Categories/Family for anti-MRPS21 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
10,742 Da
NCBI Official Full Name
MRPS21 protein
NCBI Official Synonym Full Names
mitochondrial ribosomal protein S21
NCBI Official Symbol
MRPS21
NCBI Official Synonym Symbols
MDS016; RPMS21; MRP-S21
NCBI Protein Information
28S ribosomal protein S21, mitochondrial
UniProt Protein Name
28S ribosomal protein S21, mitochondrial
Protein Family
UniProt Gene Name
MRPS21
UniProt Synonym Gene Names
RPMS21; MRP-S21; S21mt
UniProt Entry Name
RT21_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPS21: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Ribosomal

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: mitochondrial inner membrane; mitochondrial small ribosomal subunit

Molecular Function: structural constituent of ribosome

Biological Process: mitochondrial translation; translation; organelle organization and biogenesis

Research Articles on MRPS21

Similar Products

Product Notes

The MRPS21 mrps21 (Catalog #AAA5301212) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MRPS21 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:100-1:500 ELISA: 1:40000. Researchers should empirically determine the suitability of the MRPS21 mrps21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRPS21, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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