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Immunohistochemistry (IHC) (Anti-MRPL46 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Rabbit MRPL46 Polyclonal Antibody | anti-MRPL46 antibody

Rabbit Polyclonal (IgG) to Human MRPL46

Gene Names
MRPL46; LIECG2; P2ECSL; C15orf4
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
MRPL46; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human MRPL46; Anti-MRPL46 Antibody (aa111-160) IHC-plus; C15orf4; L46mt; MRP-L46; LIECG2; p2ECSL; Human MRPL46; anti-MRPL46 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MRPL46 Antibody detects endogenous levels of total MRPL46 protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
279
Applicable Applications for anti-MRPL46 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA (1:40000), IHC-P (5 ug/ml), WB (1:500 - 1:1000)
Target Species
Human
Immunogen Description
Synthetic peptide from human MRPL46 (aa111-160).
Immunogen
MRPL46 antibody was raised against synthetic peptide from human MRPL46 (aa111-160).
Antigen Modification
aa111-160
Preparation and Storage
Store at -20 degree C for up to one year.

Immunohistochemistry (IHC)

(Anti-MRPL46 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-MRPL46 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.)

Western Blot (WB)

(Western blot of extracts from HeLa cells, using MRPL46 Antibody. The lane on the right is treated with the synthesized peptide.)

Western Blot (WB) (Western blot of extracts from HeLa cells, using MRPL46 Antibody. The lane on the right is treated with the synthesized peptide.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
31,705 Da
NCBI Official Full Name
39S ribosomal protein L46, mitochondrial
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L46
NCBI Official Symbol
MRPL46
NCBI Official Synonym Symbols
LIECG2; P2ECSL; C15orf4
NCBI Protein Information
39S ribosomal protein L46, mitochondrial; L46mt; MRP-L46
UniProt Protein Name
39S ribosomal protein L46, mitochondrial
Protein Family
UniProt Gene Name
MRPL46
UniProt Synonym Gene Names
C15orf4; LIECG2; L46mt; MRP-L46
UniProt Entry Name
RM46_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPL46: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Protein type: Ribosomal; Translation; Mitochondrial

Chromosomal Location of Human Ortholog: 15q25.3

Cellular Component: nucleoplasm; mitochondrion; mitochondrial inner membrane; ribosome; cell junction

Molecular Function: hydrolase activity

Biological Process: mitochondrial translation; organelle organization and biogenesis

Research Articles on MRPL46

Similar Products

Product Notes

The MRPL46 mrpl46 (Catalog #AAA243366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human MRPL46 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MRPL46 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA (1:40000), IHC-P (5 ug/ml), WB (1:500 - 1:1000). Researchers should empirically determine the suitability of the MRPL46 mrpl46 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRPL46, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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