Rabbit MRPL37 Polyclonal Antibody | anti-MRPL37 antibody

MRPL37 (Mitochondrial Ribosomal Protein L37, L37mt, MRPL2, RPML2, MRP-L2, MRP-L37) (HRP)

Cat. Num. AAA6427270

• Gene Names: MRPL37; L37mt; MRPL2; RPML2; MRP-L2; MRP-L37
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: MRPL37; Polyclonal Antibody; MRPL37 (Mitochondrial Ribosomal Protein L37; L37mt; MRPL2; RPML2; MRP-L2; MRP-L37) (HRP); anti-MRPL37 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes MRPL37. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-MRPL37 antibody: Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: IHC: 1:50-1:200; WB: 1:200-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human MRPL37.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of mouse tissues, using MRPL37 antibody.)

Product Categories/Family for anti-MRPL37 antibody

Antibodies; Mitochondrial Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 152083350
• NCBI GeneID: 51253
• UniProt Accession #: Q9BZE1; Q96Q67; Q9BWR1; Q9P0P3
• Molecular Weight: 423
• NCBI Official Full Name: 39S ribosomal protein L37, mitochondrial
• NCBI Official Synonym Full Names: mitochondrial ribosomal protein L37
• NCBI Official Symbol: MRPL37
• NCBI Official Synonym Symbols: L37mt; MRPL2; RPML2; MRP-L2; MRP-L37
• NCBI Protein Information: 39S ribosomal protein L37, mitochondrial; L2mt; ribosomal protein, mitochondrial, L2; 39S ribosomal protein L2, mitochondrial
• UniProt Protein Name: 39S ribosomal protein L37, mitochondrial
• Protein Family: 39S ribosomal protein
• UniProt Gene Name: MRPL37
• UniProt Synonym Gene Names: MRPL2; RPML2; L37mt; MRP-L37; L2mt; MRP-L2
• UniProt Entry Name: RM37_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPL37: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Protein type: Translation; Ribosomal; Mitochondrial

Chromosomal Location of Human Ortholog: 1p32.1

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial ribosome

Molecular Function: structural constituent of ribosome

Biological Process: mitochondrial translation; translation; organelle organization and biogenesis