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Western Blot (WB) (Western blot analysis of ABCC1 antibody (C-term) in Ramos cell line lysates (35ug/lane). ABCC1 (arrow) was detected using the purified Pab.)

Rabbit anti-Human MRP Polyclonal Antibody | anti-MRP antibody

MRP, CT (Multidrug Resistance-associated Protein 1, ATP-binding Cassette Sub-family C Member 1, Leukotriene C(4) Transporter, LTC4 Transporter, MRP1, ABCC1) (MaxLight 490)

Gene Names
ABCC1; MRP; ABCC; GS-X; MRP1; ABC29
Reactivity
Human
Applications
Western Blot
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
MRP; Polyclonal Antibody; CT (Multidrug Resistance-associated Protein 1; ATP-binding Cassette Sub-family C Member 1; Leukotriene C(4) Transporter; LTC4 Transporter; MRP1; ABCC1) (MaxLight 490); anti-MRP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human ABCC1.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight490.
Applicable Applications for anti-MRP antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the C-terminal region of human ABCC1 (KLH).
Conjugate
MaxLight490
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of ABCC1 antibody (C-term) in Ramos cell line lysates (35ug/lane). ABCC1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of ABCC1 antibody (C-term) in Ramos cell line lysates (35ug/lane). ABCC1 (arrow) was detected using the purified Pab.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of NCI-H292 cells using ABCC1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of NCI-H292 cells using ABCC1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-MRP antibody
References
1. Siedlinski, M., Pharmacogenet. Genomics 19(9), 675-684 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
172,640 Da
NCBI Official Full Name
multidrug resistance-associated protein 1
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
NCBI Official Symbol
ABCC1
NCBI Official Synonym Symbols
MRP; ABCC; GS-X; MRP1; ABC29
NCBI Protein Information
multidrug resistance-associated protein 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporte
UniProt Protein Name
Multidrug resistance-associated protein 1
Protein Family
UniProt Gene Name
ABCC1
UniProt Synonym Gene Names
MRP; MRP1; LTC4 transporter
UniProt Entry Name
MRP1_HUMAN

Uniprot Description

ABCC1: a multi-pass membrane protein. A multidrug resistance member of the ABC transporter family that confers resistance to anticancer drugs. A multi-pass membrane protein. Exports sphingosine-1-phosphate (S1P), a potent inflammatory mediator, from mast cells during mast cell-mediated immune responses. Nine alternatively spliced human isoforms have been reported.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family; Transporter

Chromosomal Location of Human Ortholog: 16p13.1

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATPase activity; ATP binding

Biological Process: response to drug; vitamin metabolic process; transport; cobalamin metabolic process; arachidonic acid metabolic process; leukotriene metabolic process; transmembrane transport; water-soluble vitamin metabolic process

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Product Notes

The MRP abcc1 (Catalog #AAA6487519) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRP, CT (Multidrug Resistance-associated Protein 1, ATP-binding Cassette Sub-family C Member 1, Leukotriene C(4) Transporter, LTC4 Transporter, MRP1, ABCC1) (MaxLight 490) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MRP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:50-1:100 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MRP abcc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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