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Western Blot (WB) (Western blot analysis of lysates from HT-1080, K562 cell line (from left to right), using MRGPRX3 Antibody (N-term). MBS9205920 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)

Rabbit anti-Human MRGPRX3 Polyclonal Antibody | anti-MRGPRX3 antibody

MRGPRX3 Antibody (N-term)

Gene Names
MRGPRX3; GPCR; MRGX3; SNSR1; SNSR2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MRGPRX3; Polyclonal Antibody; MRGPRX3 Antibody (N-term); Mas-related G-protein coupled receptor member X3; Sensory neuron-specific G-protein coupled receptor 1/2; MRGX3; SNSR1; SNSR2; anti-MRGPRX3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MRGPRX3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 9-43 amino acids from the N-terminal region of human MRGPRX3.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Length
322
Applicable Applications for anti-MRGPRX3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of lysates from HT-1080, K562 cell line (from left to right), using MRGPRX3 Antibody (N-term). MBS9205920 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)

Western Blot (WB) (Western blot analysis of lysates from HT-1080, K562 cell line (from left to right), using MRGPRX3 Antibody (N-term). MBS9205920 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Related Product Information for anti-MRGPRX3 antibody
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
Product Categories/Family for anti-MRGPRX3 antibody
References
Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Martin A.L.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36483
NCBI Official Full Name
mas-related G-protein coupled receptor member X3
NCBI Official Synonym Full Names
MAS-related GPR, member X3
NCBI Official Symbol
MRGPRX3
NCBI Official Synonym Symbols
GPCR; MRGX3; SNSR1; SNSR2
NCBI Protein Information
mas-related G-protein coupled receptor member X3
UniProt Protein Name
Mas-related G-protein coupled receptor member X3
UniProt Gene Name
MRGPRX3
UniProt Synonym Gene Names
MRGX3; SNSR1; SNSR2
UniProt Entry Name
MRGX3_HUMAN

NCBI Description

This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009]

Uniprot Description

MRGPRX3: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

Research Articles on MRGPRX3

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Product Notes

The MRGPRX3 mrgprx3 (Catalog #AAA9205920) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRGPRX3 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MRGPRX3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MRGPRX3 mrgprx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRGPRX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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