Western Blot (WB)
(Western blot analysis MPHOSPH8 using COLO205 whole cell lysates)
Rabbit MPHOSPH8 Polyclonal Antibody | anti-MPHOSPH8 antibody
MPHOSPH8 Antibody
Western Blot (WB)
(Western blot analysis MPHOSPH8 using COLO205 whole cell lysates)
Western Blot (WB)
(Western blot analysis MPHOSPH8 using COLO205 whole cell lysates)
NCBI and Uniprot Product Information
Uniprot Description
MPHOSPH8: Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 13q12.11
Cellular Component: cytoplasm; nuclear heterochromatin; nucleolus; nucleus; plasma membrane; ubiquitin ligase complex
Molecular Function: methylated histone residue binding; protein binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity
Biological Process: negative regulation of transcription, DNA-dependent
Research Articles on MPHOSPH8
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Product Notes
The MPHOSPH8 mphosph8 (Catalog #AAA9419449) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MPHOSPH8 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MPHOSPH8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000-3000. Researchers should empirically determine the suitability of the MPHOSPH8 mphosph8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MPHOSPH8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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