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Western Blot (WB) (Western blot analysis of Mov10 expression in (1) 293 cell lysate; (2) NIH/3T3 cell lysate.)

Rabbit Mov10 Polyclonal Antibody | anti-Mov10 antibody

Mov10 Rabbit pAb

Gene Names
MOV10; gb110; fSAP113
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
Mov10; Polyclonal Antibody; Mov10 Rabbit pAb; gb110; MOV 10; anti-Mov10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mov10 Antibody detects endogenous levels of total Mov10
Purity/Purification
Affinity purified
Form/Format
Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applicable Applications for anti-Mov10 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
A synthesized peptide derived from human Mov10
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at +4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of Mov10 expression in (1) 293 cell lysate; (2) NIH/3T3 cell lysate.)

Western Blot (WB) (Western blot analysis of Mov10 expression in (1) 293 cell lysate; (2) NIH/3T3 cell lysate.)
Related Product Information for anti-Mov10 antibody
MOV10 may be an helicase with an important function in development and/or control of cell proliferation. RNA silencing processes are guided by small RNAs known as siRNAs and microRNAs (miRNAs). They reside in ribonucleoprotein complexes, which guide the cleavage of complementary mRNAs or affect stability and translation of partial complementary mRNAs.
Product Categories/Family for anti-Mov10 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
1003
NCBI Official Full Name
Putative helicase MOV-10
NCBI Official Synonym Full Names
Mov10 RISC complex RNA helicase
NCBI Official Symbol
MOV10
NCBI Official Synonym Symbols
gb110; fSAP113
NCBI Protein Information
putative helicase MOV-10; moloney leukemia virus 10 protein; Mov10, Moloney leukemia virus 10, homolog; functional spliceosome-associated protein 113
UniProt Protein Name
Putative helicase MOV-10
Protein Family
UniProt Gene Name
MOV10
UniProt Synonym Gene Names
KIAA1631
UniProt Entry Name
MOV10_HUMAN

Uniprot Description

MOV10: Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; RNA processing; Helicase; EC 3.6.4.13; Spliceosome

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: extracellular space; cytosol

Molecular Function: protein binding; helicase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; Notch signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; miRNA-mediated gene silencing, mRNA cleavage; innate immune response

Research Articles on Mov10

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Product Notes

The Mov10 mov10 (Catalog #AAA4757267) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mov10 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Mov10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the Mov10 mov10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mov10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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