Western Blot (WB)
(Western blot analysis of lysate from mouse liver tissue, using mouse Dpys Antibody (C-term). MBS9208489 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Rabbit MOUSE Dpys Polyclonal Antibody | anti-Dpys antibody
MOUSE Dpys Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysate from mouse liver tissue, using mouse Dpys Antibody (C-term). MBS9208489 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Western Blot (WB)
(Western blot analysis of lysate from mouse liver tissue, using mouse Dpys Antibody (C-term). MBS9208489 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Chang C.J.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
NCBI and Uniprot Product Information
Uniprot Description
DPYS: Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6- dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. Defects in DPYS are the cause of dihydropyrimidinase deficiency (DHPD). DHPD is an autosomal recessive disorder characterized by dihydropyrimidinuria and associated with a variable clinical phenotype: epileptic or convulsive attacks, dysmorphic features and severe developmental delay, and congenital microvillous atrophy. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.
Protein type: EC 3.5.2.2; Other Amino Acids Metabolism - beta-alanine; Hydrolase; Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis
Cellular Component: cytoplasm; cytosol
Molecular Function: thymine binding; amino acid binding; dihydropyrimidinase activity; hydrolase activity; zinc ion binding; uracil binding; metal ion binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; phosphoprotein binding
Biological Process: uracil metabolic process; beta-alanine metabolic process; uracil catabolic process; thymine catabolic process; protein homooligomerization; pyrimidine base catabolic process; protein homotetramerization
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Product Notes
The Dpys dpys (Catalog #AAA9208489) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MOUSE Dpys Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MOUSE Dpys can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Dpys dpys for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MOUSE Dpys, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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