Rabbit anti-Human Monocarboxylate Transporter 5 Polyclonal Antibody | anti-SLC16A4 antibody
Monocarboxylate Transporter 5 (MCT5, MOT5)
Gene Names
SLC16A4; MCT4; MCT5
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Monocarboxylate Transporter 5; Polyclonal Antibody; Monocarboxylate Transporter 5 (MCT5; MOT5); Anti -Monocarboxylate Transporter 5 (MCT5; anti-SLC16A4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Monocarboxylate Transporter 5 (MCT5/MOT5). Reactivity with other members of the MCT family is unlikely because the immunogen shows no significant sequence homology with other MCTs.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.
Applicable Applications for anti-SLC16A4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide per well.
Western Blot: 1-5ug/ml using ECL.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide per well.
Western Blot: 1-5ug/ml using ECL.
Immunogen
Synthetic peptide corresponding to a 19aa sequence within the cytoplasmic domain #4, near the C-terminus of human MCT5 conjugated to KLH. Species Sequence Homology: mouse MCT5, 65%.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-SLC16A4 antibody
Lactic acid transport is mediated by a group of proton-linked membrane transporters called monocarboxylic acid transporters (MCTs). At least 9 MCT-related proteins (MCT1-9) have been identified in mammals that are expressed in a tissue specific manner.
MCT5/SLC16A4 (mouse 468-aa, human 487-aa, chromosome 1p13.1) shares 25% sequence homology with MCT1, but it has much shorter C-terminus than other MCTs. MCT5 has an Alu insertion even in the 3'-UTR and a truncated C-terminus. High expression of MCT5 has been observed in placenta. According to new nomenclature, the old MCT4 has now been reclassified as MCT5.
MCT5/SLC16A4 (mouse 468-aa, human 487-aa, chromosome 1p13.1) shares 25% sequence homology with MCT1, but it has much shorter C-terminus than other MCTs. MCT5 has an Alu insertion even in the 3'-UTR and a truncated C-terminus. High expression of MCT5 has been observed in placenta. According to new nomenclature, the old MCT4 has now been reclassified as MCT5.
Product Categories/Family for anti-SLC16A4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,022 Da
NCBI Official Full Name
monocarboxylate transporter 5 isoform 1
NCBI Official Synonym Full Names
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
NCBI Official Symbol
SLC16A4
NCBI Official Synonym Symbols
MCT4; MCT5
NCBI Protein Information
monocarboxylate transporter 5; MCT 4; MCT 5; OTTHUMP00000013008; OTTHUMP00000013284; OTTHUMP00000229648; monocarboxylate transporter 4; solute carrier family 16 member 4; solute carrier family 16 (monocarboxylic acid transporters), member 4
UniProt Protein Name
Monocarboxylate transporter 5
Protein Family
UniProt Gene Name
SLC16A4
UniProt Synonym Gene Names
MCT4; MCT5
UniProt Entry Name
MOT5_HUMAN
Uniprot Description
SLC16A4: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p13.3
Cellular Component: membrane; integral to plasma membrane; integral to membrane
Molecular Function: monocarboxylic acid transmembrane transporter activity; symporter activity
Biological Process: monocarboxylic acid transport
Research Articles on SLC16A4
Similar Products
Product Notes
The SLC16A4 slc16a4 (Catalog #AAA618530) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Monocarboxylate Transporter 5 (MCT5, MOT5) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Monocarboxylate Transporter 5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng control peptide per well. Western Blot: 1-5ug/ml using ECL. Researchers should empirically determine the suitability of the SLC16A4 slc16a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Monocarboxylate Transporter 5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
