Rabbit MOCS3 Polyclonal Antibody | anti-MOCS3 antibody

Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) MOCS3 Polyclonal Antibody

• Gene Names: mocs3; zgc:55696
• Reactivity: Danio rerio (Zebrafish)(Brachydanio rerio)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: MOCS3; Polyclonal Antibody; Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) MOCS3 Polyclonal Antibody; MOCS3 Antibody; Adenylyltransferase and sulfurtransferase MOCS3; Molybdenum cofactor synthesis protein 3; [Includes: Molybdopterin-synthase adenylyltransferase; EC 2.7.7.80; Adenylyltransferase MOCS3; Sulfur carrier protein MOCS2A adenylyltransferase; Molybdopterin-synthase sulfurtransferase; EC 2.8.1.11; Sulfur carrier protein MOCS2A sulfurtransferase; Sulfurtransferase MOCS3)] mocs3 uba4 zgc:55696; anti-MOCS3 antibody

• Host: Rabbit
• Reactivity: Danio rerio (Zebrafish)(Brachydanio rerio)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-MOCS3 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) mocs3 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 41056017
• NCBI GeneID: 393095
• NCBI Accession #: NP_956421.1
• NCBI GenBank Nucleotide #: NM_200127.1
• UniProt Accession #: Q8AWD2; Q6IQE7
• Molecular Weight: 50,798 Da
• NCBI Official Full Name: adenylyltransferase and sulfurtransferase MOCS3
• NCBI Official Synonym Full Names: molybdenum cofactor synthesis 3
• NCBI Official Symbol: mocs3
• NCBI Official Synonym Symbols: zgc:55696
• NCBI Protein Information: adenylyltransferase and sulfurtransferase MOCS3
• UniProt Protein Name: Adenylyltransferase and sulfurtransferase MOCS3
• UniProt Gene Name: mocs3
• UniProt Synonym Gene Names: uba4

Uniprot Description

Plays a central role in 2-thiolation of mcm5S2U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions ().