Rabbit anti-Human MMRN2 Polyclonal Antibody | anti-MMRN2 antibody
MMRN2, CT (MMRN2, EMILIN3, Multimerin-2, EMILIN-3, Elastin microfibril interface located protein 3, EndoGlyx-1 p125/p140 subunit)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Western Blot (WB)
(MMRN2 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MMRN2 antibody detected the MMRN2 protein (arrow).)
Immunohistochemistry (IHC)
(MMRN2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMRN2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012]
Uniprot Description
MMRN2: Heteromer of p110, p125, p140 and p200 subunits; disulfide-linked.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q23.2
Cellular Component: extracellular space; basement membrane
Molecular Function: protein binding
Biological Process: negative regulation of vascular endothelial growth factor receptor signaling pathway; angiogenesis
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Product Notes
The MMRN2 mmrn2 (Catalog #AAA641226) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMRN2, CT (MMRN2, EMILIN3, Multimerin-2, EMILIN-3, Elastin microfibril interface located protein 3, EndoGlyx-1 p125/p140 subunit) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MMRN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Western Blot, Immunohistochemistry, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50. Researchers should empirically determine the suitability of the MMRN2 mmrn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMRN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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