Western Blot (WB)
(Western blot detection of MMP9 in Rat lung cell lysates using MMP9 antibody. Observed band size:92kDa.)
Rabbit anti-Mouse, Rat MMP9 Polyclonal Antibody | anti-MMP9 antibody
MMP9 Rabbit pAb
IHC: 1:100
IP: 1:20
Western Blot (WB)
(Western blot detection of MMP9 in Rat lung cell lysates using MMP9 antibody. Observed band size:92kDa.)
Western Blot (WB)
(Western blot detection of MMP9 in Rat lung cell lysates using MMP9 antibody. Observed band size:92kDa.)
NCBI and Uniprot Product Information
Uniprot Description
MMP9: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1. Activated by 4-aminophenylmercuric acetate and phorbol ester. Up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. Produced by normal alveolar macrophages and granulocytes. Inhibited by histatin-3 1/24 (histatin-5). Inhibited by ECM1. Belongs to the peptidase M10A family.
Protein type: Protease; Secreted; Motility/polarity/chemotaxis; EC 3.4.24.35; Secreted, signal peptide
Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; protein complex; extracellular region
Molecular Function: peptidase activity; identical protein binding; zinc ion binding; hydrolase activity; metallopeptidase activity; fibronectin binding; metal ion binding; metalloendopeptidase activity; endopeptidase activity; protein complex binding
Biological Process: positive regulation of keratinocyte migration; response to drug; ossification; extracellular matrix organization and biogenesis; positive regulation of apoptosis; positive regulation of leukocyte migration; tissue remodeling; positive regulation of synaptic plasticity; proteolysis; protein oligomerization; collagen catabolic process; positive regulation of angiogenesis; negative regulation of fibroblast proliferation; response to oxidative stress; leukocyte migration; skeletal development; embryo implantation; transformation of host cell by virus
Research Articles on MMP9
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Product Notes
The MMP9 mmp9 (Catalog #AAA4756771) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMP9 Rabbit pAb reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MMP9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunoprecipitation (IP). WB: 1:1000 IHC: 1:100 IP: 1:20. Researchers should empirically determine the suitability of the MMP9 mmp9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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