Western Blot (WB)
(Western Blot (WB) analysis of MMP28 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264. 7 whole cell lysate Lane3:PC12 whole cell lysate)
Rabbit MMP28 Polyclonal Antibody | anti-MMP28 antibody
MMP28 Polyclonal Antibody
Gene Names
MMP28; MM28; MMP25; MMP-25; MMP-28; EPILYSIN
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
MMP28; Polyclonal Antibody; MMP28 Polyclonal Antibody; Matrix metalloproteinase-28; MMP-28; Epilysin; MMP25; UNQ1893; PRO4339; anti-MMP28 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MMP28 polyclonal antibody detects endogenous levels of MMP28 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
520
Applicable Applications for anti-MMP28 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human MMP28
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of MMP28 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264. 7 whole cell lysate Lane3:PC12 whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of MMP28 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Raw264. 7 whole cell lysate Lane3:PC12 whole cell lysate)
Related Product Information for anti-MMP28 antibody
Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein that belongs to the peptidase M10A family. Matrix metalloproteinase proteins are responsible for the breakdown of the extracellular matrix which is important for normal physiological processes such as tissue remodeling, reproduction and embryonic development. Epilysin is produced by proliferating keratinocytes and is responsible for mediating the degradation of casein. Its expression is upregulated in response to injury of the skin suggesting that Epilysin may be involved in tissue repair and homeostasis. In addition, Epilysin may function predominantly in the nervous system. Incubation of Epilysin with rat embryonic brain tissue results in the degradation of myelin proteins. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation. This suggests that Epilysin plays an evolutionarily conserved role in neural development and may be involved in modulating the axonal-glial extracellular environment.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 59kDa
NCBI Official Full Name
matrix metalloproteinase-28 isoform 1 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 28
NCBI Official Symbol
MMP28
NCBI Official Synonym Symbols
MM28; MMP25; MMP-25; MMP-28; EPILYSIN
NCBI Protein Information
matrix metalloproteinase-28
UniProt Protein Name
Matrix metalloproteinase-28
Protein Family
UniProt Gene Name
MMP28
UniProt Synonym Gene Names
MMP25; MMP-28
UniProt Entry Name
MMP28_HUMAN
NCBI Description
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Research Articles on MMP28
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Product Notes
The MMP28 mmp28 (Catalog #AAA3006972) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMP28 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MMP28 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the MMP28 mmp28 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP28, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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