Rabbit anti-Human MMP23B Polyclonal Antibody | anti-MMP23B antibody

Rabbit Polyclonal (IgG) to Human MMP23B

Cat. Num. AAA247933

• Gene Names: MMP23B; MIFR; MMP22; MIFR-1; MMP23A
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Immunoaffinity Purified
• Synonyms: MMP23B; Polyclonal Antibody; Rabbit Polyclonal (IgG) to Human MMP23B; Anti-MMP23B Antibody (C-Terminus) IHC-plus; CA-MMP; Matrix metallopeptidase 23B; Matrix metalloproteinase 23B; Matrix metalloproteinase 22; Matrix metalloproteinase-21; Matrix metalloproteinase-22; Matrix metalloproteinase-23; MIFR-2; MMP-21; MMP23A; MIFR; MIFR-1; Femalysin; Human MMP23B; anti-MMP23B antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Immunoaffinity Purified
• Form/Format: 10 mM PBS, pH 7.4, BSA, sodium azide.
• Sequence Length: 390

• Applicable Applications for anti-MMP23B antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
• Application Notes: IHC-P (1:50), WB
• Target Species: Human
• Immunogen Description: A synthetic peptide derived from C-terminus of human MMP-23 protein.
• Immunogen Type: Synthetic peptide
• Immunogen: MMP23B antibody was raised against a synthetic peptide derived from C-terminus of human MMP-23 protein.
• Antigen Modification: C-Terminus
• Preparation and Storage: Store at 2 degree C to 8 degree C degrees. Do not freeze.

Immunohistochemistry (IHC)

(Anti-MMP23B antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.)

Related Product Information for anti-MMP23B antibody

MMP23A and MMP23B, two Metallopeptidase type proteases, are type II membrane-anchored zymogens that are proteolytically processed at a conserved motif and converted into secretory and mature enzymes. The proteins contain prepro, catalytic, cysteine-rich, interleukin-1 receptor-related and proline-rich domains. The MMP23A and MMP23B genes have been reported to express multiple mRNAs, some of which are derived by alternative splicing.

Product Categories/Family for anti-MMP23B antibody

Family: Protease; Subfamily: Metallopeptidase Other

NCBI and Uniprot Product Information

• NCBI GI #: 5902004
• NCBI GeneID: 8510
• NCBI Accession #: NP_008914.1
• NCBI GenBank Nucleotide #: NM_006983.1
• Molecular Weight: 46,305 Da
• NCBI Official Full Name: matrix metalloproteinase-23
• NCBI Official Synonym Full Names: matrix metallopeptidase 23B
• NCBI Official Symbol: MMP23B
• NCBI Official Synonym Symbols: MIFR; MMP22; MIFR-1; MMP23A
• NCBI Protein Information: matrix metalloproteinase-23; MMP-21; MMP-22; MMP-23; femalysin; matrix metalloproteinase 22; matrix metalloproteinase-21; matrix metalloproteinase-22; matrix metalloproteinase 23B; matrix metalloproteinase in the female reproductive tract
• UniProt Protein Name: Matrix metalloproteinase-23
• UniProt Gene Name: MMP23A
• UniProt Synonym Gene Names: MMP21; MMP-23; MMP-21; MMP-22
• UniProt Entry Name: MMP23_HUMAN

NCBI Description

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]

Uniprot Description

MMP23B: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum. Belongs to the peptidase M10A family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Protease; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 1p36.3

Cellular Component: proteinaceous extracellular matrix; endoplasmic reticulum membrane; integral to membrane; intracellular

Molecular Function: metallopeptidase activity; zinc ion binding; metalloendopeptidase activity

Biological Process: reproduction; proteolysis