Rabbit anti-Human MMP13 Polyclonal Antibody | anti-mmp13a antibody

MMP13, ID (MMP13, Collagenase 3, Matrix metalloproteinase-13)

Cat. Num. AAA647316

• Gene Names: mmp13a; mmp13; cb1034
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: MMP13; Polyclonal Antibody; ID (MMP13; Collagenase 3; Matrix metalloproteinase-13); Anti -MMP13; anti-mmp13a antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-mmp13a antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunofluorescence: 1:10-50; Immunohistochemistry: 1:10-50
• Immunogen: MMP13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-282 amino acids from the Central region of human MMP13.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in K562 cell line lysates (35ug/lane) using MBS647316. This demonstrates that MBS647316 detected the MMP13 protein (arrow).)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma using MBS647316 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS647316 for immunohistochemistry.)

Immunofluorescence (IF)

(Confocal immunofluorescent analysis with Hela cells using MBS647316 followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)

Related Product Information for anti-mmp13a antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Product Categories/Family for anti-mmp13a antibody

Antibodies; Abs to Matrix Metalloproteinases

NCBI and Uniprot Product Information

• NCBI GI #: 41393163
• NCBI GeneID: 387293
• NCBI Accession #: NP_958911.1
• NCBI GenBank Nucleotide #: NM_201503.1
• NCBI Official Full Name: matrix metalloproteinase 13a
• NCBI Official Synonym Full Names: matrix metalloproteinase 13a
• NCBI Official Symbol: mmp13a
• NCBI Official Synonym Symbols: mmp13; cb1034
• NCBI Protein Information: matrix metalloproteinase 13a; MMPLg; MMPLh