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Western Blot (WB) (MMP10 rabbit polyclonal antibody. Western Blot analysis of MMP10 expression in mouse lung.)

Rabbit anti-Human, Mouse MMP10 Polyclonal Antibody | anti-MMP10 antibody

MMP10 (Stromelysin-2, SL-2, Matrix Metalloproteinase-10, MMP-10, Transin-2, STMY2) (HRP)

Gene Names
MMP10; SL-2; STMY2
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
MMP10; Polyclonal Antibody; MMP10 (Stromelysin-2; SL-2; Matrix Metalloproteinase-10; MMP-10; Transin-2; STMY2) (HRP); anti-MMP10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human MMP10. Species Crossreactivity: mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-MMP10 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human MMP10, aa1-476 (NP_002416.1).
Immunogen Sequence
MMHLAFLVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVKQFRRKDSNLIVKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MMP10 rabbit polyclonal antibody. Western Blot analysis of MMP10 expression in mouse lung.)

Western Blot (WB) (MMP10 rabbit polyclonal antibody. Western Blot analysis of MMP10 expression in mouse lung.)

Western Blot (WB)

(Western Blot analysis of MMP10 expression in transfected 293T cell line by MMP10 polyclonal antibody. Lane 1: MMP10 transfected lysate (54.2kD). Lane 2: Non-transfected lysate.)

Western Blot (WB) (Western Blot analysis of MMP10 expression in transfected 293T cell line by MMP10 polyclonal antibody. Lane 1: MMP10 transfected lysate (54.2kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-MMP10 antibody
MMP10 is a Metallopeptidase M10A type protease. Stromelysin2/MMP10 is a member of a gene family of metalloproteinases involved in extracellular matrix remodeling in normal and diseased processes. It degrades collagen and many non-collagenous components of the extracellular matrix including fibronectin, gelatins of type I, III, IV, and V and may play a role in the activation of latent procollagenase.
Product Categories/Family for anti-MMP10 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,151 Da
NCBI Official Full Name
stromelysin-2 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 10 (stromelysin 2)
NCBI Official Symbol
MMP10
NCBI Official Synonym Symbols
SL-2; STMY2
NCBI Protein Information
stromelysin-2; MMP-10; transin 2; transin-2; stromelysin 2; matrix metalloprotease 10; matrix metalloproteinase-10; matrix metalloproteinase 10 (stromelysin 2)
UniProt Protein Name
Stromelysin-2
Protein Family
UniProt Gene Name
MMP10
UniProt Synonym Gene Names
STMY2; SL-2; MMP-10
UniProt Entry Name
MMP10_HUMAN

NCBI Description

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Uniprot Description

MMP10: Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. Belongs to the peptidase M10A family.

Protein type: Secreted; Secreted, signal peptide; Extracellular matrix; EC 3.4.24.22; Protease

Chromosomal Location of Human Ortholog: 11q22.3

Cellular Component: extracellular space; proteinaceous extracellular matrix; extracellular region

Molecular Function: zinc ion binding; metalloendopeptidase activity; calcium ion binding

Biological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; proteolysis; regulation of cell migration

Research Articles on MMP10

Similar Products

Product Notes

The MMP10 mmp10 (Catalog #AAA6385603) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMP10 (Stromelysin-2, SL-2, Matrix Metalloproteinase-10, MMP-10, Transin-2, STMY2) (HRP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MMP10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MMP10 mmp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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