Western Blot (WB)
(Western blot analysis of MMAA Antibody (N-term) in mouse liver tissue lysates (35ug/lane). MMAA (arrow) was detected using the purified Pab.)
Rabbit anti-Human, Mouse MMAA Polyclonal Antibody | anti-MMAA antibody
MMAA, NT (MMAA, Methylmalonic aciduria type A protein, mitochondrial) (APC)
Gene Names
MMAA; cblA
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
MMAA; Polyclonal Antibody; NT (MMAA; Methylmalonic aciduria type A protein; mitochondrial) (APC); mitochondrial; anti-MMAA antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-MMAA antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
MMAA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63~92 amino acids from the N-terminal region of human MMAA.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(Western blot analysis of MMAA Antibody (N-term) in mouse liver tissue lysates (35ug/lane). MMAA (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of MMAA Antibody (N-term) in mouse liver tissue lysates (35ug/lane). MMAA (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(MMAA Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.)
Immunohistochemistry (IHC)
(MMAA Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.)
Related Product Information for anti-MMAA antibody
The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria.
Product Categories/Family for anti-MMAA antibody
References
Honjo, R.S., et al. Genet Test Mol Biomarkers 13(2):181-183(2009). Merinero, B., et al. J. Inherit. Metab. Dis. 31(1):55-66(2008). Horster, F., et al. Pediatr. Res. 62(2):225-230(2007). Padovani, D., et al. J. Biol. Chem. 281(26):17838-17844(2006). Lerner-Ellis, J.P., et al. Hum. Mutat. 24(6):509-516(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,538 Da
NCBI Official Full Name
methylmalonic aciduria type A protein, mitochondrial
NCBI Official Synonym Full Names
methylmalonic aciduria (cobalamin deficiency) cblA type
NCBI Official Symbol
MMAA
NCBI Official Synonym Symbols
cblA
NCBI Protein Information
methylmalonic aciduria type A protein, mitochondrial
UniProt Protein Name
Methylmalonic aciduria type A protein, mitochondrial
Protein Family
UniProt Gene Name
MMAA
UniProt Entry Name
MMAA_HUMAN
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Product Notes
The MMAA mmaa (Catalog #AAA6321230) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MMAA, NT (MMAA, Methylmalonic aciduria type A protein, mitochondrial) (APC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MMAA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:50-100 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MMAA mmaa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMAA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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