Rabbit anti-Human MLYCD Polyclonal Antibody | anti-MLYCD antibody

MLYCD (Malonyl-CoA Decarboxylase, Mitochondrial, MCD) (Biotin)

Cat. Num. AAA6385557

• Gene Names: MLYCD; MCD
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MLYCD; Polyclonal Antibody; MLYCD (Malonyl-CoA Decarboxylase; Mitochondrial; MCD) (Biotin); anti-MLYCD antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human MLYCD.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-MLYCD antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human MLYCD, aa1-493 (NP_036345.2).
• Immunogen Sequence: MRGFGPGLTARRLLPLRLPPRPPGPRLASGQAAGALERAMDELLRRAVPPTPAYELREKTPAPAEGQCADFVSFYGGLAETAQRAELLGRLARGFGVDHGQVAEQSAGVLHLRQQQREAAVLLQAEDRLRYALVPRYRGLFHHISKLDGGVRFLVQLRADLLEAQALKLVEGPDVREMNGVLKGMLSEWFSSGFLNLERVTWHSPCEVLQKISEAEAVHPVKNWMDMKRRVGPYRRCYFFSHCSTPGEPLVVLHVALTGDISSNIQAIVKEHPPSETEEKNKITAAIFYSISLTQQGLQGVELGTFLIKRVVKELQREFPHLGVFSSLSPIPGFTKWLLGLLNSQTKEHGRNELFTDSECKEISEITGGPINETLKLLLSSSEWVQSEKLVRALQTPLMRLCAWYLYGEKHRGYALNPVANFHLQNGAVLWRINWMADVSLRGITGSCGLMANYRYFLEETGPNSTSYLGSKIIKASEQVLSLVAQFQKNSKL
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of MLYCD expression in transfected 293T cell line by MLYCD polyclonal antibody. Lane 1: MLYCD transfected lysate (55kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-MLYCD antibody

MLYCD, malonyl CoA decarboxylase, catalyzes the conversion of malonyl CoA to acetyl CoA and carbon dioxide. In fatty acid biosynthesis MCD selectively removes malonyl CoA and thus assures that methyl malonyl CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl CoA, which is generated by the peroxisomal beta oxidation of odd chain length dicarboxylic fatty acids.

Product Categories/Family for anti-MLYCD antibody

Antibodies; Enzymes; Decarboxylase

NCBI and Uniprot Product Information

• NCBI GI #: 110349750
• NCBI GeneID: 23417
• NCBI Accession #: NP_036345.2
• NCBI GenBank Nucleotide #: NM_012213.2
• Molecular Weight: 50,946 Da
• NCBI Official Full Name: malonyl-CoA decarboxylase, mitochondrial
• NCBI Official Synonym Full Names: malonyl-CoA decarboxylase
• NCBI Official Symbol: MLYCD
• NCBI Official Synonym Symbols: MCD
• NCBI Protein Information: malonyl-CoA decarboxylase, mitochondrial; malonyl coenzyme A decarboxylase
• Protein Family: Malonyl-CoA decarboxylase

NCBI Description

The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008]