Rabbit anti-Human MLL2 Polyclonal Antibody | anti-MLL2 antibody
MLL2 Polyclonal Antibody
Gene Names
KMT2D; ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114
Reactivity
Human
Applications
Immunohistochemistry
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MLL2; Polyclonal Antibody; MLL2 Polyclonal Antibody; Histone-lysine N-methyltransferase MLL2; EC 2.1.1.43; ALL1-related protein; Lysine N-methyltransferase 2D; KMT2D; Myeloid/lymphoid or mixed-lineage leukemia protein 2; ALR; MLL4; anti-MLL2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Sequence Length
5537
Applicable Applications for anti-MLL2 antibody
Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-p: 1:50-300
Immunogen
Synthesized peptide derived from human protein. at AA range: 1430-1510
Preparation and Storage
Store at-20 degree C for 1 year.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
609
NCBI Official Full Name
histone-lysine N-methyltransferase 2D
NCBI Official Synonym Full Names
lysine methyltransferase 2D
NCBI Official Symbol
KMT2D
NCBI Official Synonym Symbols
ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114
NCBI Protein Information
histone-lysine N-methyltransferase 2D
UniProt Protein Name
Histone-lysine N-methyltransferase 2D
UniProt Gene Name
KMT2D
UniProt Synonym Gene Names
ALR; MLL2; MLL4; Lysine N-methyltransferase 2D
NCBI Description
The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]
Uniprot Description
Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.
Research Articles on MLL2
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Product Notes
The MLL2 kmt2d (Catalog #AAA8530228) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MLL2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MLL2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. IHC-p: 1:50-300. Researchers should empirically determine the suitability of the MLL2 kmt2d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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