Western Blot (WB)
(MKX Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MKX antibody detected the MKX protein (arrow).)
Rabbit MKX Polyclonal Antibody | anti-MKX antibody
MKX Antibody (N-term)
Gene Names
MKX; IFRX; IRXL1; C10orf48
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MKX; Polyclonal Antibody; MKX Antibody (N-term); Homeobox protein Mohawk; C10orf48; IRXL1; anti-MKX antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MKX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human MKX.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
46-75
Sequence Length
352
Applicable Applications for anti-MKX antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(MKX Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MKX antibody detected the MKX protein (arrow).)
Western Blot (WB)
(MKX Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MKX antibody detected the MKX protein (arrow).)
Related Product Information for anti-MKX antibody
MKX is a member of an Iroquois (IRX) family-related class
of 'three-amino acid loop extension' (TALE) atypical homeobox
proteins characterized by 3 additional amino acids in the loop
region between helix I and helix II of the homeodomain (Anderson et
al., 2006 [PubMed 16408284]).
of 'three-amino acid loop extension' (TALE) atypical homeobox
proteins characterized by 3 additional amino acids in the loop
region between helix I and helix II of the homeodomain (Anderson et
al., 2006 [PubMed 16408284]).
References
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Anderson, D.M., et al. Dev. Dyn. 235(3):792-801(2006)
Weinmann, A., et al. Int. J. Mol. Med. 16(3):443-448(2005)
Robertson, N.G., et al. Genomics 23(1):42-50(1994)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Anderson, D.M., et al. Dev. Dyn. 235(3):792-801(2006)
Weinmann, A., et al. Int. J. Mol. Med. 16(3):443-448(2005)
Robertson, N.G., et al. Genomics 23(1):42-50(1994)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39331
NCBI Official Full Name
homeobox protein Mohawk
NCBI Official Synonym Full Names
mohawk homeobox
NCBI Official Symbol
MKX
NCBI Official Synonym Symbols
IFRX; IRXL1; C10orf48
NCBI Protein Information
homeobox protein Mohawk
UniProt Protein Name
Homeobox protein Mohawk
Protein Family
UniProt Gene Name
MKX
UniProt Synonym Gene Names
C10orf48; IRXL1
UniProt Entry Name
MKX_HUMAN
NCBI Description
The protein encoded by this gene is an IRX family-related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Jun 2011]
Uniprot Description
MKX: May act as a morphogenetic regulator of cell adhesion. Belongs to the TALE/IRO homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 10p12.1
Cellular Component: nucleus
Biological Process: transcription from RNA polymerase II promoter; muscle development; collagen fibril organization; positive regulation of collagen biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; negative regulation of myoblast differentiation
Research Articles on MKX
Similar Products
Product Notes
The MKX mkx (Catalog #AAA9213405) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 46-75. The MKX Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's MKX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MKX mkx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MKX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
