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Western Blot (WB) (Western blot-MKRN3 Polyclonal Antibody)

Rabbit anti-Human, Mouse MKRN3 Polyclonal Antibody | anti-MKRN3 antibody

MKRN3 Polyclonal Antibody

Gene Names
MKRN3; CPPB2; D15S9; RNF63; ZFP127; ZNF127
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity Purification
Synonyms
MKRN3; Polyclonal Antibody; MKRN3 Polyclonal Antibody; CPPB2; D15S9; RNF63; ZFP127; ZNF127; makorin ring finger protein 3; anti-MKRN3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
3.71 mg/ml (varies by lot)
Sequence Length
507
Applicable Applications for anti-MKRN3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human MKRN3 (NP_005655.1).
Immunogen Sequence
MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPVAPVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFFEAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSSETERKQMAVGSGLRFCYYASRGVCFRGESCMY
Positive Samples
Mouse Kidney
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot-MKRN3 Polyclonal Antibody)

Western Blot (WB) (Western blot-MKRN3 Polyclonal Antibody)
Related Product Information for anti-MKRN3 antibody
The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 55kDa
Observed: 56kDa
NCBI Official Full Name
probable E3 ubiquitin-protein ligase makorin-3
NCBI Official Synonym Full Names
makorin ring finger protein 3
NCBI Official Symbol
MKRN3
NCBI Official Synonym Symbols
CPPB2; D15S9; RNF63; ZFP127; ZNF127
NCBI Protein Information
probable E3 ubiquitin-protein ligase makorin-3
UniProt Protein Name
Probable E3 ubiquitin-protein ligase makorin-3
UniProt Gene Name
MKRN3
UniProt Synonym Gene Names
D15S9; RNF63; ZNF127

NCBI Description

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

MKRN3: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Protein type: EC 6.3.2.-; EC 6.3.2.19; Ubiquitin conjugating system; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 15q11.2

Cellular Component: intracellular ribonucleoprotein complex

Molecular Function: identical protein binding; metal ion binding; protein binding; transferase activity

Biological Process: protein ubiquitination

Disease: Prader-willi Syndrome; Precocious Puberty, Central, 2

Research Articles on MKRN3

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Product Notes

The MKRN3 mkrn3 (Catalog #AAA9140699) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MKRN3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MKRN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MKRN3 mkrn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MKRN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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