Western Blot (WB)
(MKLN1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MKLN1 antibody detected the MKLN1 protein (arrow).)
Rabbit MKLN1 Polyclonal Antibody | anti-MKLN1 antibody
MKLN1 Antibody (Center)
Gene Names
MKLN1; TWA2
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MKLN1; Polyclonal Antibody; MKLN1 Antibody (Center); Muskelin; anti-MKLN1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MKLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-326 amino acids from the Central region of human MKLN1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.35 (varies by lot)
Sequence Positions
300-326
Sequence Length
528
Applicable Applications for anti-MKLN1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(MKLN1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MKLN1 antibody detected the MKLN1 protein (arrow).)
Western Blot (WB)
(MKLN1 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MKLN1 antibody detected the MKLN1 protein (arrow).)
Related Product Information for anti-MKLN1 antibody
Muskelin is an intracellular protein that acts as a
mediator of cell spreading and cytoskeletal responses to the
extracellular matrix component thrombospondin I (MIM 188060) (Adams
et al., 1998 [PubMed 9724633]).
mediator of cell spreading and cytoskeletal responses to the
extracellular matrix component thrombospondin I (MIM 188060) (Adams
et al., 1998 [PubMed 9724633]).
Product Categories/Family for anti-MKLN1 antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Shyn, S.I., et al. Mol. Psychiatry (2009) In press :
Valiyaveettil, M., et al. J. Cell Biol. 182(4):727-739(2008)
Kobayashi, N., et al. Gene 396(2):236-247(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Shyn, S.I., et al. Mol. Psychiatry (2009) In press :
Valiyaveettil, M., et al. J. Cell Biol. 182(4):727-739(2008)
Kobayashi, N., et al. Gene 396(2):236-247(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84768
NCBI Official Full Name
muskelin isoform 1
NCBI Official Synonym Full Names
muskelin 1, intracellular mediator containing kelch motifs
NCBI Official Symbol
MKLN1
NCBI Official Synonym Symbols
TWA2
NCBI Protein Information
muskelin
UniProt Protein Name
Muskelin
Protein Family
UniProt Gene Name
MKLN1
UniProt Entry Name
MKLN1_HUMAN
NCBI Description
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Uniprot Description
MKLN1: Acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component THBS1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Cell adhesion
Chromosomal Location of Human Ortholog: 7q32
Cellular Component: ruffle; cell cortex; cytosol
Biological Process: regulation of cell shape; cell-matrix adhesion; actin cytoskeleton reorganization; signal transduction
Research Articles on MKLN1
Similar Products
Product Notes
The MKLN1 mkln1 (Catalog #AAA9202591) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 300-326. The MKLN1 Antibody (Center) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's MKLN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MKLN1 mkln1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MKLN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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