Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MKK6 antibody (Ser207))
Rabbit MKK6 Polyclonal Antibody | anti-MKK6 antibody
MKK6 Antibody (Ser207)
Gene Names
MAP2K6; MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; SAPKK-3
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Affinity Chromatography
Synonyms
MKK6; Polyclonal Antibody; MKK6 Antibody (Ser207); Rabbit Polyclonal MKK6 Antibody (Ser207); Polyclonal MKK6 antibody; Anti-MKK6 antibody; Dual specificity mitogen-activated protein kinase kinase 6 antibody; MAP kinase kinase 6 antibody; MAP2K6 antibody; MAPK/ERK kinase 6 antibody; MAPKK 6 antibody; MAPKK6 antibody; MEK 6 antibody; MEK6 antibody; mitogen-activated protein kinase kinase 6 antibody; MKK6 antibody; MP2K6 antibody; PRKMK6 antibody; protein kinase mitogen-activated kinase 6 (MAP kinase kinase 6) antibody; SAPKK3 antibody; anti-MKK6 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
MKK6 antibody (Ser207) detects endogenous levels of MKK6 only when phosphorylated at serine207
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
334
Applicable Applications for anti-MKK6 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:100
IF: 1:100-200
IHC: 1:50-1:100
IF: 1:100-200
Immunogen
MKK6 antibody was raised in Rabbit using a synthesized phosphopeptide derived from human MKK6 around the phosphorylation site of serine 207 (V-D-SP-V-A) as the immunogen.
Cross-Reactivity
Rat
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MKK6 antibody (Ser207))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MKK6 antibody (Ser207))
Western Blot (WB)
(Western blot analysis of extract from MDA-MB-435 cells untreated or treated with UV, using MKK6 antibody and MKK6 antibody (Ser207) (Lanes 3 and 4))
Western Blot (WB)
(Western blot analysis of extract from MDA-MB-435 cells untreated or treated with UV, using MKK6 antibody and MKK6 antibody (Ser207) (Lanes 3 and 4))
Related Product Information for anti-MKK6 antibody
MKK6 is a dual-specificity protein kinase of the STE7 family. Activates p38 MAP kinase by phosphorylating a Thr and a Tyr residue in the activation loop. Is activated by cytokines and environmental stress in vivo.
Product Categories/Family for anti-MKK6 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
MAP kinase kinase 6
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase 6
NCBI Official Symbol
MAP2K6
NCBI Official Synonym Symbols
MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; SAPKK-3
NCBI Protein Information
dual specificity mitogen-activated protein kinase kinase 6
Protein Family
NCBI Description
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
Research Articles on MKK6
Similar Products
Product Notes
The MKK6 (Catalog #AAA5313586) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MKK6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:100-200. Researchers should empirically determine the suitability of the MKK6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MKK6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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