Western Blot (WB)
(Western blot analysis of lysates from human spleen tissue lysate, HepG2, SH-SY5Y, NCCIT cell line, mouse liver tissue lysate (from left to right), using MIXL1 Antibody (C-term). MBS9212265 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Rabbit anti-Human, mouse MIXL1 Polyclonal Antibody | anti-MIXL1 antibody
MIXL1 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysates from human spleen tissue lysate, HepG2, SH-SY5Y, NCCIT cell line, mouse liver tissue lysate (from left to right), using MIXL1 Antibody (C-term). MBS9212265 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from human spleen tissue lysate, HepG2, SH-SY5Y, NCCIT cell line, mouse liver tissue lysate (from left to right), using MIXL1 Antibody (C-term). MBS9212265 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.)
Robb L.,et al.Dev. Dyn. 219:497-504(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Mossman A.K.,et al.Stem Cells Dev. 14:656-663(2005).
NCBI and Uniprot Product Information
NCBI Description
Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]).[supplied by OMIM, Mar 2008]
Uniprot Description
MIXL1: Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression. Belongs to the paired homeobox family.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 1q42.12
Cellular Component: nuclear chromatin
Molecular Function: protein homodimerization activity
Biological Process: transcription, DNA-dependent; gut development; heart development; positive regulation of transcription from RNA polymerase II promoter; gastrulation; hemopoietic progenitor cell differentiation; cell migration involved in gastrulation; endoderm development
Research Articles on MIXL1
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Product Notes
The MIXL1 mixl1 (Catalog #AAA9212265) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MIXL1 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MIXL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:500-1:1000. Researchers should empirically determine the suitability of the MIXL1 mixl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MIXL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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