Rabbit anti-Human Mitochondrial Open Reading Frame Of The 12S rRNA-c Polyclonal Antibody | anti-MOTS-c antibody
Mitochondrial Open Reading Frame Of The 12S rRNA-c (MOTS-c) Polyclonal Antibody
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Mitochondrial Open Reading Frame Of The 12S rRNA-c; Polyclonal Antibody; Mitochondrial Open Reading Frame Of The 12S rRNA-c (MOTS-c) Polyclonal Antibody; anti-MOTS-c antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against MOTS-c. It has been selected for its ability to recognize MOTS-c in immunohistochemical staining and western blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4 containing 0.02% NaN3, 50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence Length
16
Applicable Applications for anti-MOTS-c antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western Blot: 1:50-400
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunoglobulin Type
IgG
Conjugate
No Conjugate
Cross Reactivity
Human
Organism Species
Human
Fragment
Synthetic Peptide, MOTS-c conjugated to OVA
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2085768
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
2,175 Da
NCBI Official Full Name
MOTS-c
UniProt Protein Name
MOTS-c
UniProt Entry Name
A0A0C5B5G6_HUMAN
Uniprot Description
MT-RNR1: Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity. {ECO:0000269|PubMed:25738459}
Disease: Deafness, Nonsyndromic Sensorineural, Mitochondrial
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Product Notes
The MOTS-c (Catalog #AAA2032472) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mitochondrial Open Reading Frame Of The 12S rRNA-c (MOTS-c) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Mitochondrial Open Reading Frame Of The 12S rRNA-c can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western Blot: 1:50-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the MOTS-c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mitochondrial Open Reading Frame Of The 12S rRNA-c, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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