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Western Blot (WB) (Western blot analysis of MINA53 expression in A431 cell lysate.)

Rabbit anti-Human, Mouse MINA53 Polyclonal Antibody | anti-MINA53 antibody

Anti-MINA53 Rabbit pAb

Gene Names
RIOX2; ROX; MDIG; MINA; NO52; JMJD10; MINA53
Reactivity
Human, Mouse
Applications
Western Blot, Immunocytochemistry, Immunofluorescence
Purity
Affinity Chromatography
Synonyms
MINA53; Polyclonal Antibody; Anti-MINA53 Rabbit pAb; Histone lysine demethylase MINA; MDIG; MINA; NO52; ROX; anti-MINA53 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
MINA53 Antibody detects endogenous levels of total MINA53
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
465
Applicable Applications for anti-MINA53 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
ICC/IF: 1:50-1:200
Immunogen
A synthesized peptide derived from human MINA53
Subcellular Location
Nucleus; Nucleolus
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of MINA53 expression in A431 cell lysate.)

Western Blot (WB) (Western blot analysis of MINA53 expression in A431 cell lysate.)
Related Product Information for anti-MINA53 antibody
Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53kDa
NCBI Official Full Name
ribosomal oxygenase 2 isoform a
NCBI Official Synonym Full Names
ribosomal oxygenase 2
NCBI Official Symbol
RIOX2
NCBI Official Synonym Symbols
ROX; MDIG; MINA; NO52; JMJD10; MINA53
NCBI Protein Information
ribosomal oxygenase 2
UniProt Protein Name
Ribosomal oxygenase 2
UniProt Gene Name
RIOX2
UniProt Synonym Gene Names
ROX

NCBI Description

MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008]

Uniprot Description

Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.

Research Articles on MINA53

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Product Notes

The MINA53 riox2 (Catalog #AAA4750755) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MINA53 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MINA53 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). WB: 1:500-1:2000 ICC/IF: 1:50-1:200. Researchers should empirically determine the suitability of the MINA53 riox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MINA53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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