Western Blot (WB)
(Western blot analysis of MIIP Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane).MIIP (arrow) was detected using the purified Pab.)
Rabbit anti-Human MIIP Polyclonal Antibody | anti-MIIP antibody
MIIP Antibody (C-term)
Gene Names
MIIP; IIP45
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MIIP; Polyclonal Antibody; MIIP Antibody (C-term); Migration and invasion-inhibitory protein; IGFBP2-binding protein; Invasion-inhibitory protein 45; IIp45; IIP45; anti-MIIP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MIIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the C-terminal region of human MIIP.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
275-303
Sequence Length
359
Applicable Applications for anti-MIIP antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(Western blot analysis of MIIP Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane).MIIP (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of MIIP Antibody (C-term) in ZR-75-1 cell line lysates (35ug/lane).MIIP (arrow) was detected using the purified Pab.)
Related Product Information for anti-MIIP antibody
MIIP inhibits glioma cells invasion and down-regulates adhesion-and motility-associated genes such as NFKB2 and ICAM1. MIIP exhibits opposing effects to IGFBP2 on cell invasion.
Product Categories/Family for anti-MIIP antibody
References
Wu, Y., et al. J. Biol. Chem. 285(6):3554-3560(2010) Song, F., et al. Cancer Res. 70(3):1024-1032(2010) Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42824
NCBI Official Full Name
migration and invasion-inhibitory protein
NCBI Official Synonym Full Names
migration and invasion inhibitory protein
NCBI Official Symbol
MIIP
NCBI Official Synonym Symbols
IIP45
NCBI Protein Information
migration and invasion-inhibitory protein
UniProt Protein Name
Migration and invasion-inhibitory protein
Protein Family
UniProt Gene Name
MIIP
UniProt Synonym Gene Names
IIP45; IIp45
UniProt Entry Name
MIIP_HUMAN
NCBI Description
This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers. [provided by RefSeq, Sep 2011]
Uniprot Description
MIIP: Inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. Exhibits opposing effects to IGFBP2 on cell invasion. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 1p36.22
Research Articles on MIIP
Similar Products
Product Notes
The MIIP miip (Catalog #AAA9202563) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 275-303. The MIIP Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MIIP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MIIP miip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MIIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
