Rabbit anti-Human MIA MIA Polyclonal Antibody | anti-MIA antibody
MIA antibody
Reactivity
Human MIA
Applications
ELISA, Western Blot
Synonyms
MIA; Polyclonal Antibody; MIA antibody; Polyclonal MIA; Anti-MIA; Cartilage-derived retinoic acid-sensitive; Melanoma Inhibitory Activity; CD-RAP; anti-MIA antibody
Host
Rabbit
Reactivity
Human MIA
Clonality
Polyclonal
Specificity
Human MIA
Form/Format
Lyophilized from PBS, pH 7.2.
Applicable Applications for anti-MIA antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Biological Significance
MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for melanoma metastasis as well as a potential marker for rheumatoid arthritis.
Immunogen
MIA antibody was raised in rabbit using highly pure recombinant human MIA as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-MIA antibody
Affinity purified Rabbit polyclonal MIA antibody
Product Categories/Family for anti-MIA antibody
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Product Notes
The MIA (Catalog #AAA535879) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MIA antibody reacts with Human MIA and may cross-react with other species as described in the data sheet. AAA Biotech's MIA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the MIA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MIA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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