Western Blot (WB)
(WB Suggested Anti-MGC3207 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Liver)
Rabbit anti-Human MGC3207 Polyclonal Antibody | anti-MRI1 antibody
MGC3207 antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-MGC3207 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Liver)
Western Blot (WB)
(WB Suggested Anti-MGC3207 AntibodyTitration: 1.0 ug/mlPositive Control: Fetal Liver)
Target Description: MGC3207 catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, MGC3207 promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.
NCBI and Uniprot Product Information
NCBI Description
This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016]
Uniprot Description
MRI1: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover. Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Isomerase; EC 5.3.1.23
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: cell projection; cytoplasm; nucleolus; cytosol
Molecular Function: identical protein binding; S-methyl-5-thioribose-1-phosphate isomerase activity
Biological Process: methionine salvage; sulfur amino acid metabolic process; methionine biosynthetic process from S-adenosylmethionine; polyamine metabolic process
Research Articles on MRI1
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Product Notes
The MRI1 mri1 (Catalog #AAA3214808) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MGC3207 antibody - N-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MGC3207 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the MRI1 mri1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ARDLADVAAR EAEREGATEE AVRERRETEL CEHWEEHTRQ RELPLRGPLG. It is sometimes possible for the material contained within the vial of "MGC3207, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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