Western Blot (WB)
(Anti-MEOX2 rabbit polyclonal antibody at 1:500 dilution Lane A: NIH3T3 Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lane C: MCF7 Whole Cell Lysate Lane D: 293T Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:37 kDa (We are unsure as to the identity of these extra bands.))
Rabbit anti-Human MEOX2 Polyclonal Antibody | anti-MEOX2 antibody
Anti-MEOX2 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Western Blot
Purity
Protein A & Antigen Affinity
Synonyms
MEOX2; Polyclonal Antibody; Anti-MEOX2 Antibody; Rabbit Polyclonal; MEOX2 Antibody; Rabbit PAb; Antigen Affinity Purified; Anti-GAX Antibody; Anti-MEOX 2 Antibody; Anti-MOX2 Antibody; anti-MEOX2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human MEOX2
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-MEOX2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
E Coli-derived Human MEOX2 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human MEOX2 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
(Anti-MEOX2 rabbit polyclonal antibody at 1:500 dilution Lane A: NIH3T3 Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lane C: MCF7 Whole Cell Lysate Lane D: 293T Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:37 kDa (We are unsure as to the identity of these extra bands.))
Western Blot (WB)
(Anti-MEOX2 rabbit polyclonal antibody at 1:500 dilution Lane A: NIH3T3 Whole Cell Lysate Lane B: HeLa Whole Cell Lysate Lane C: MCF7 Whole Cell Lysate Lane D: 293T Whole Cell Lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:37 kDa (We are unsure as to the identity of these extra bands.))
Related Product Information for anti-MEOX2 antibody
The MEOX2 homeoprotein inhibits nuclear factor-kappaB (NF-kappaB) signalling and EC activation in response to serum and proangiogenic factors. The homeodomain transcription factor MEOX2 is an important regulator of vascular cell proliferation and is a direct transcriptional activator of both p21(CIP1/WAF1) and p16(INK4a). MEOX1 and MEOX2 are partially functionally redundant during development, suggesting that they regulate similar target genes in vivo. In human umbilical vein endothelial cells, MEOX2 upregulates cyclin-dependent kinase inhibitor expression, resulting in increased senescence and decreased proliferation. MEOX2 mutation is a potential cause of familial Alzheimer's disease. MEOX2 could constitute an interesting prognostic biomarker, especially for lower grade glioma.
References
Wang Y, et al. (2019) Generation of induced pluripotent stem cell line (zzui0013-a) from a 65-year-old patient with a novel meox2 gene mutation in alzheimer's disease. Stem Cell Res 34 101366.Gohn CR, et al. (2017) Mesenchyme homeobox 2 enhances migration of endothelial colony forming cells exposed to intrauterine diabetes mellitus. J Cell Physiol 232 (7): 1885-1892.Douville JM, et al. (2011) Mechanisms of meox1 and meox2 regulation of the cyclin dependent kinase inhibitors p21 and p16 in vascular endothelial cells. PLoS One 6 (12): e29099.
Similar Products
Product Notes
The MEOX2 (Catalog #AAA8109677) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MEOX2 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MEOX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MEOX2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MEOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
