Western Blot (WB)
(Western blot analysis of MEMO1 using MCF7 whole cell lysates)
Rabbit anti-Human MEMO1 Polyclonal Antibody | anti-MEMO1 antibody
MEMO1 Antibody
Gene Names
MEMO1; MEMO; C2orf4; CGI-27; NS5ATP7
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
MEMO1; Polyclonal Antibody; MEMO1 Antibody; C21orf19-like protein; C2orf4; CGI 27; DKFZp434I0135; FLJ25031; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; Mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; Memo-1; memo1; MEMO1_HUMAN; NS5ATP7; Protein MEMO1; anti-MEMO1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
MEMO1 antibody detects endogenous levels of total MEMO1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
274
Applicable Applications for anti-MEMO1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human MEMO1
Predicted Cross Reactivity
Pig, Zebrafish, Bovine, Xenopus
Similarity
Pig (100%), Zebrafish (90%), Bovine (100%), Xenopus (80%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of MEMO1 using MCF7 whole cell lysates)
Western Blot (WB)
(Western blot analysis of MEMO1 using MCF7 whole cell lysates)
Related Product Information for anti-MEMO1 antibody
Function: May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
Subunit Structure: Interacts with ERBB2 phosphorylated on 'Tyr-1248'.
Similarity: Belongs to the MEMO1 family.
Subunit Structure: Interacts with ERBB2 phosphorylated on 'Tyr-1248'.
Similarity: Belongs to the MEMO1 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 33 kDa
Predicted: 34 kDa
Predicted: 34 kDa
NCBI Official Full Name
protein MEMO1 isoform 2
NCBI Official Synonym Full Names
mediator of cell motility 1
NCBI Official Symbol
MEMO1
NCBI Official Synonym Symbols
MEMO; C2orf4; CGI-27; NS5ATP7
NCBI Protein Information
protein MEMO1
UniProt Protein Name
Protein MEMO1
Protein Family
UniProt Gene Name
MEMO1
UniProt Synonym Gene Names
C2orf4; MEMO; NS5ATP7; HCV NS5A-transactivated protein 7; Mediator of cell motility 1; Memo-1
Uniprot Description
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
Research Articles on MEMO1
Similar Products
Product Notes
The MEMO1 memo1 (Catalog #AAA9608774) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MEMO1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MEMO1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the MEMO1 memo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MEMO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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