Western Blot (WB)
(Western blot analysis of MEKKK6 expression in HEK293T (A), HepG2 (B), HeLa (C) whole cell lysates.)
Rabbit MEKKK6 Polyclonal Antibody | anti-MINK1 antibody
Anti-MEKKK6 Antibody
Western Blot (WB)
(Western blot analysis of MEKKK6 expression in HEK293T (A), HepG2 (B), HeLa (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of MEKKK6 expression in HEK293T (A), HepG2 (B), HeLa (C) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of MEKKK6 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of MEKKK6 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016]
Uniprot Description
MINK: a protein kinase of the STE20 family. Studies of the mouse ortholog indicate increased expression during postnatal mouse cerebral development. Activates JNK and the p38 pathways. Three splicing isoforms have been described.
Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, STE; EC 2.7.11.1; STE group; STE20 family; MSN subfamily
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: axon; cell junction; cytoplasm; cytosol; dendrite; Golgi apparatus; postsynaptic density; postsynaptic membrane
Molecular Function: ATP binding; MAP kinase kinase kinase kinase activity; protein binding; protein kinase activity; protein serine/threonine kinase activity
Biological Process: actin cytoskeleton reorganization; dendrite morphogenesis; JNK cascade; microvillus biogenesis; multicellular organismal development; negative thymic T cell selection; neurite morphogenesis; positive regulation of JNK cascade; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of apoptosis; regulation of cell migration; regulation of cell-cell adhesion; regulation of cell-matrix adhesion; regulation of mitotic cell cycle; response to stress; synaptic transmission
Research Articles on MINK1
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Product Notes
The MINK1 mink1 (Catalog #AAA8242149) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MEKKK6 Antibody reacts with Human, Mouse, Rat, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's MEKKK6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200). Researchers should empirically determine the suitability of the MINK1 mink1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MEKKK6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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