Goat mei-41 Polyclonal Antibody | anti-mei-41 antibody
Goat anti-mei-41 (Drosophila melanogaster) Antibody
Gene Names
mei-41; 4252; atr; ATR; CG4252; DmATR; DmelCG4252; Dmmei41; fs(1)M37; mei-195; Mei-41; Mei-41/DATR; mei41; MEI41; MEI41/FRP1; meiP41; mus(1)103; mus(1)104; mus-103; mus-104; mus103; mus104
Reactivity
Expected from sequence similarity: Drosophila
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
mei-41; Polyclonal Antibody; Goat anti-mei-41 (Drosophila melanogaster) Antibody; meiotic 41; Dmel; CG4252; 4252; ATR; DmATR; Dmel\CG4252; Dmmei41; MEI41; MEI41/FRP1; Mei-41; Mei-41/DATR; atr; fs(1)M37; mei-195; mei41; meiP41; mus(1)103; mus(1)104; mus-103; mus-104; mus103; mus104; ATM-RAD3 related; CG4252-PA; drosophil; 4252 antibody; ATM-RAD3 related antibody; ATR antibody; atr antibody; CG4252 antibody; CG4252-PA antibody; DmATR antibody; Dmel antibody; Dmel\CG4252 antibody; Dmmei41 antibody; drosophila ATR antibody; fs(1)M37 antibody; mei-195 antibody; MEI41 antibody; mei41 antibody; Mei-41 antibody; Mei-41/DATR antibody; MEI41/FRP1 antibody; mei-41-PA antibody; meiotic 41 antibody; meiotic-41 antibody; meiP41 antibody; mus(1)103 antibody; mus(1)104 antibody; mus103 antibody; mus-103 antibody; mus104 antibody; mus-104 antibody; mei-41 antibody; mei-41 (Drosophila melanogaster); anti-mei-41 antibody
Host
Goat
Reactivity
Expected from sequence similarity: Drosophila
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
DPHCAIEDIKVPLEQ
Sequence Length
2517
Applicable Applications for anti-mei-41 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
Immunogen
Peptide with sequence DPHCAIEDIKVPLEQ, from the internal region of the protein sequence according to NP_523369.2.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
289,330 Da
NCBI Official Full Name
meiotic 41
NCBI Official Synonym Full Names
meiotic 41
NCBI Official Symbol
mei-41
NCBI Official Synonym Symbols
4252; atr; ATR; CG4252; DmATR; DmelCG4252; Dmmei41; fs(1)M37; mei-195; Mei-41; Mei-41/DATR; mei41; MEI41; MEI41/FRP1; meiP41; mus(1)103; mus(1)104; mus-103; mus-104; mus103; mus104
NCBI Protein Information
CG4252 gene product from transcript CG4252-RA
UniProt Protein Name
Serine/threonine-protein kinase ATR
UniProt Gene Name
mei-41
UniProt Synonym Gene Names
ATR homolog; dATR
UniProt Entry Name
ATR_DROME
Uniprot Description
Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination. Phosphorylates grp/CHK1. Phosphorylates 'Ser-137' of histone variant H2AX/H2AV at sites of DNA damage, thereby regulating DNA damage response mechanism. Essential for the DNA damage checkpoint in larval imaginal disks and neuroblasts and for the DNA replication checkpoint in the embryo. Has also an essential role during early nuclear divisions in embryos, where it is required to delay mitosis in response to incomplete DNA replication. Also plays an important role during meiosis, where it may monitor double-strand-break repair during meiotic crossing over, to regulate the progression of prophase I, and to enforce metaphase I delay observed at the end of oogenesis.
Research Articles on mei-41
Similar Products
Product Notes
The mei-41 mei-41 (Catalog #AAA422928) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-mei-41 (Drosophila melanogaster) Antibody reacts with Expected from sequence similarity: Drosophila and may cross-react with other species as described in the data sheet. AAA Biotech's mei-41 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product. Researchers should empirically determine the suitability of the mei-41 mei-41 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: DPHCAIEDIK VPLEQ. It is sometimes possible for the material contained within the vial of "mei-41, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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