Rabbit anti-Mouse MEG11 Polyclonal Antibody | anti-MEG11 antibody

MEG11, NT (MEGF11, KIAA1781, Multiple epidermal growth factor-like domains protein 11) (Azide free) (HRP)

Cat. Num. AAA6320137

• Reactivity: Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MEG11; Polyclonal Antibody; NT (MEGF11; KIAA1781; Multiple epidermal growth factor-like domains protein 11) (Azide free) (HRP); MEGF11; Multiple epidermal growth factor-like domains protein 11; anti-MEG11 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-MEG11 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: MEG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human MEG11.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MEG11 Antibody (N-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the MEG11 antibody detected the MEG11 protein (arrow).)

Product Categories/Family for anti-MEG11 antibody

Antibodies; Growth Factors; Cytokines

References

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010). Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010). Suzuki, E., et al. Exp. Cell Res. 313(11):2451-2464(2007). Lim, J., et al. Cell 125(4):801-814(2006). Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 181336739
• NCBI GeneID: 84465
• NCBI Accession #: NP_115821.2
• NCBI GenBank Nucleotide #: NM_032445.2
• UniProt Accession #: A6BM72; Q17R86; Q6UXS5; Q8ND91; Q96KG6
• Molecular Weight: 15,467 Da
• NCBI Official Full Name: multiple epidermal growth factor-like domains protein 11
• NCBI Official Synonym Full Names: multiple EGF-like-domains 11
• NCBI Official Symbol: MEGF11
• NCBI Protein Information: multiple epidermal growth factor-like domains protein 11
• UniProt Protein Name: Multiple epidermal growth factor-like domains protein 11
• UniProt Gene Name: MEGF11
• UniProt Synonym Gene Names: KIAA1781; Multiple EGF-like domains protein 11
• UniProt Entry Name: MEG11_HUMAN

Uniprot Description

MEGF11: May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements. Belongs to the MEGF family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q22.31

Cellular Component: basolateral plasma membrane; integral to membrane

Biological Process: homotypic cell-cell adhesion