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Western Blot (Western Blot analysis using MEF2C antibodyMEF2C antibody used at 0.2-1 ug/ml to detect target protein.)

Rabbit MEF2C Polyclonal Antibody | anti-MEF2C antibody

MEF2C antibody

Gene Names
Mef2c; Mef2; AV011172; 5430401D19Rik; 9930028G15Rik
Applications
Western Blot
Synonyms
MEF2C; Polyclonal Antibody; MEF2C antibody; Polyclonal MEF2C; Anti-MEF2C; MEFC-2; MEFC 2; anti-MEF2C antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 100 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
432
Applicable Applications for anti-MEF2C antibody
Western Blot (WB)
Application Notes
WB: 2.5 ug/ml
Biological Significance
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation.
Cross-Reactivity
Mouse, Rat, Dog, Human, Pig, Zebrafish, African Clawed Frog, Bovine
Immunogen
MEF2C antibody was raised in rabbit using the N terminal of MEF2C as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.

Western Blot

(Western Blot analysis using MEF2C antibodyMEF2C antibody used at 0.2-1 ug/ml to detect target protein.)

Western Blot (Western Blot analysis using MEF2C antibodyMEF2C antibody used at 0.2-1 ug/ml to detect target protein.)
Related Product Information for anti-MEF2C antibody
Rabbit polyclonal MEF2C antibody
Product Categories/Family for anti-MEF2C antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,168 Da
NCBI Official Full Name
myocyte-specific enhancer factor 2C isoform 2
NCBI Official Synonym Full Names
myocyte enhancer factor 2C
NCBI Official Symbol
Mef2c
NCBI Official Synonym Symbols
Mef2; AV011172; 5430401D19Rik; 9930028G15Rik
NCBI Protein Information
myocyte-specific enhancer factor 2C
UniProt Protein Name
Myocyte-specific enhancer factor 2C
UniProt Gene Name
Mef2c
UniProt Entry Name
MEF2C_MOUSE

Uniprot Description

MEF2C: transcription factor of the MADS family which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in myogenesis, neurogenesis and in the development of cortical architecture. Three splice-variant isoforms have been described.

Protein type: DNA-binding; Transcription factor

Cellular Component: nucleoplasm; sarcomere; protein complex; intracellular membrane-bound organelle; cytoplasm; nuclear speck; intracellular; cytosol; nucleus

Molecular Function: protein dimerization activity; RNA polymerase II transcription factor activity, enhancer binding; protein binding; miRNA binding; transcription activator binding; DNA binding; AT DNA binding; sequence-specific DNA binding; protein heterodimerization activity; histone deacetylase binding; chromatin binding; transcription factor activity

Biological Process: cardiac muscle hypertrophy; positive regulation of transcription, DNA-dependent; heart development; multicellular organismal development; regulation of neurotransmitter secretion; regulation of synaptic plasticity; cardiac muscle cell differentiation; neuron differentiation; positive regulation of MAP kinase activity; B cell receptor signaling pathway; regulation of neuron apoptosis; positive regulation of B cell proliferation; negative regulation of ossification; chondrocyte differentiation; negative regulation of neuron apoptosis; positive regulation of cardiac muscle cell proliferation; endochondral ossification; nervous system development; skeletal muscle development; cell fate commitment; transcription, DNA-dependent; monocyte differentiation; positive regulation of skeletal muscle development; muscle cell fate determination; regulation of synaptogenesis; neuron development; positive regulation of transcription from RNA polymerase II promoter; smooth muscle cell differentiation; B cell proliferation; transcription from RNA polymerase II promoter; regulation of synaptic transmission, glutamatergic; apoptosis; ventricular cardiac muscle cell differentiation; neuron migration; regulation of synaptic activity; negative regulation of transcription from RNA polymerase II promoter; palate development; learning and/or memory; regulation of transcription, DNA-dependent; B cell homeostasis; regulation of megakaryocyte differentiation; melanocyte differentiation; germinal center formation; neural crest cell differentiation; heart looping; cell differentiation; negative regulation of epithelial cell proliferation; blood vessel development; MAPKKK cascade; embryonic viscerocranium morphogenesis; positive regulation of bone mineralization; regulation of germinal center formation; humoral immune response; positive regulation of myoblast differentiation; embryonic skeletal morphogenesis; osteoblast differentiation; positive regulation of osteoblast differentiation; neuron morphogenesis during differentiation; blood vessel remodeling; platelet formation; positive regulation of neuron differentiation; regulation of excitatory postsynaptic membrane potential

Research Articles on MEF2C

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Product Notes

The MEF2C mef2c (Catalog #AAA833479) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MEF2C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 2.5 ug/ml. Researchers should empirically determine the suitability of the MEF2C mef2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MEF2C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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